[HTML][HTML] Western diet as a trigger of Alzheimer's disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration
A Więckowska-Gacek, A Mietelska-Porowska… - Ageing research …, 2021 - Elsevier
An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …
The impact of systemic inflammation on Alzheimer's disease pathology
J Xie, L Van Hoecke, RE Vandenbroucke - Frontiers in immunology, 2022 - frontiersin.org
Alzheimer's disease (AD) is a devastating age-related neurodegenerative disorder with an
alarming increasing prevalence. Except for the recently FDA-approved Aducanumab of …
alarming increasing prevalence. Except for the recently FDA-approved Aducanumab of …
The crucial role and mechanism of insulin resistance in metabolic disease
X Zhao, X An, C Yang, W Sun, H Ji… - Frontiers in endocrinology, 2023 - frontiersin.org
Insulin resistance (IR) plays a crucial role in the development and progression of
metabolism-related diseases such as diabetes, hypertension, tumors, and nonalcoholic fatty …
metabolism-related diseases such as diabetes, hypertension, tumors, and nonalcoholic fatty …
In silico and in vivo analysis to identify the antidiabetic activity of beta sitosterol in adipose tissue of high fat diet and sucrose induced type-2 diabetic experimental …
R Ponnulakshmi, B Shyamaladevi… - Toxicology …, 2019 - Taylor & Francis
Adipose tissue is the primary site of storage for excess energy as triglyceride and it helps in
synthesizing a number of biologically active compounds that regulate metabolic …
synthesizing a number of biologically active compounds that regulate metabolic …
Obesity, hypertension, and cardiac dysfunction: novel roles of immunometabolism in macrophage activation and inflammation
AJ Mouton, X Li, ME Hall, JE Hall - Circulation research, 2020 - Am Heart Assoc
Obesity and hypertension, which often coexist, are major risk factors for heart failure and are
characterized by chronic, low-grade inflammation, which promotes adverse cardiac …
characterized by chronic, low-grade inflammation, which promotes adverse cardiac …
Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention
M Picon‐Ruiz, C Morata‐Tarifa… - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE Recent decades have seen an unprecedented rise in
obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than …
obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than …
[HTML][HTML] The long history of vitamin C: from prevention of the common cold to potential aid in the treatment of COVID-19
From Pauling's theories to the present, considerable understanding has been acquired of
both the physiological role of vitamin C and of the impact of vitamin C supplementation on …
both the physiological role of vitamin C and of the impact of vitamin C supplementation on …
Type 2 inflammation in asthma—present in most, absent in many
JV Fahy - Nature Reviews Immunology, 2015 - nature.com
Asthma is one of the most common chronic immunological diseases in humans, affecting
people from childhood to old age. Progress in treating asthma has been relatively slow and …
people from childhood to old age. Progress in treating asthma has been relatively slow and …
Obesity and its metabolic complications: the role of adipokines and the relationship between obesity, inflammation, insulin resistance, dyslipidemia and nonalcoholic …
UJ Jung, MS Choi - International journal of molecular sciences, 2014 - mdpi.com
Accumulating evidence indicates that obesity is closely associated with an increased risk of
metabolic diseases such as insulin resistance, type 2 diabetes, dyslipidemia and …
metabolic diseases such as insulin resistance, type 2 diabetes, dyslipidemia and …
[HTML][HTML] Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges
Because current therapeutics for obesity are limited and only offer modest improvements,
novel interventions are needed. Preventing obesity with time-restricted feeding (TRF; 8–9 hr …
novel interventions are needed. Preventing obesity with time-restricted feeding (TRF; 8–9 hr …