[HTML][HTML] Dysregulation of AMPA Receptor Trafficking and Intracellular Vesicular Sorting in the Prefrontal Cortex of Dopamine Transporter Knock-Out Rats

G Targa, F Mottarlini, B Rizzi, D Leo, L Caffino… - Biomolecules, 2023 - mdpi.com
Dopamine (DA) and glutamate interact, influencing neural excitability and promoting
synaptic plasticity. However, little is known regarding the molecular mechanisms underlying …

[HTML][HTML] Neurobiological Theories of Addiction: A Comprehensive Review

C Ferrer-Pérez, S Montagud-Romero… - Psychoactives, 2024 - mdpi.com
It is essential to develop theories and models that enable us to understand addiction's
genesis and maintenance, providing a theoretical and empirical framework for designing …

[HTML][HTML] The effect of CNQX on self-administration: present in nicotine, absent in methamphetamine model

M Hrickova, P Amchova… - Frontiers in Behavioral …, 2024 - frontiersin.org
Objective Addiction is a chronic disease with limited pharmacological options for
intervention. Focusing on reducing glutamate levels in the brain seems to be a promising …

Inhibition of GSDMD-dependent pyroptosis decreased methamphetamine self-administration in rats

Y Shen, X Gong, L Qian, Y Ruan, S Lin, Z Yu… - Brain, Behavior, and …, 2024 - Elsevier
It is widely believed that the activation of the central dopamine (DA) system is crucial to the
rewarding effects of methamphetamine (METH) and to the behavioral outcomes of METH …

[HTML][HTML] Restoring GABAB receptor expression in the ventral tegmental area of methamphetamine addicted mice inhibits locomotor sensitization and drug seeking …

M Hleihil, D Benke - Frontiers in Molecular Neuroscience, 2024 - frontiersin.org
Repeated exposure to psychostimulants such as methamphetamine (METH) induces
neuronal adaptations in the mesocorticolimbic dopamine system, including the ventral …

Impact of miR-29c-3p in the Nucleus Accumbens on Methamphetamine-Induced Behavioral Sensitization and Neuroplasticity-Related Proteins

H Su, L Zhu, L Su, M Li, R Wang, J Zhu, Y Chen… - International Journal of …, 2024 - mdpi.com
Methamphetamine (METH) abuse inflicts both physical and psychological harm. While our
previous research has established the regulatory role of miR-29c-3p in behavior …

Enantiomeric contributions to methamphetamine's bidirectional effects on basal and fentanyl-depressed respiration in mice

HJ Elder, DM Walentiny, PM Beardsley - Pharmacology Biochemistry and …, 2024 - Elsevier
Rationale Fentanyl remains the primary cause of fatal overdoses, and its co-use with
methamphetamine (METH) is a growing concern. We previously demonstrated that racemic …

Effect of amoxicillin/clavulanic acid in attenuating pregabalin-induced condition place preference

AM Hammad, H Amawi, FS Hall, AK Tiwari… - Behavioural Brain …, 2023 - Elsevier
Substance abuse is a worldwide problem with serious repercussions for patients and the
communities where they live. Pregabalin (Lyrica), is a medication commonly used to treat …

[HTML][HTML] The distinct roles of various neurotransmitters in modulating methamphetamine-induced conditioned place preference in relevant brain regions in mice

H Su, J Bai, Y Fan, T Sun, Y Du, Y Li, Z Wei, T Chen… - …, 2022 - journals.lww.com
Objectives Previous studies have shown that methamphetamine (METH) can induce
complex adaptive changes in the reward system in the brain, including the changes in the …

[HTML][HTML] Could immunotherapy be a hope for addiction treatment?

MCM Silva, LPS Ferreira, AD Giustina - Clinics, 2024 - SciELO Brasil
World Drug Report 2023 nd https://www. unodc. org/unodc/en/data-and-analysis/
Exsum_wdr2023. html (accessed September 27, 2023). 4. Di Chiara G, Imperato A. Drugs …