Epigenetics has the potential to explain various biological phenomena that have heretofore
defied complete explication. This review describes the various types of endogenous human …

Alternative splicing of precursor mRNA is an important mechanism that increases
transcriptomic and proteomic diversity and also post-transcriptionally regulates mRNA …

Abstract Reduced expression 1 (REX1) is a widely used pluripotency marker, but little is
known about its roles in pluripotency. Here, we show that REX1 is functionally important in …

Summary β-hydroxybutyrate (β-HB) elevation during fasting or caloric restriction is believed
to induce anti-aging effects and alleviate aging-related neurodegeneration. However …

Introduction Umbilical cord blood (UCB)-derived mesenchymal stem cells (MSCs) are self-
renewing multipotent progenitors with the potential to differentiate into multiple lineages of …

Cell-to-cell communication is a critical requirement to coordinate behaviors of the cells in a
community and thereby achieve tissue homeostasis and conservation of the multicellular …

ZNF462 haploinsufficiency is linked to Weiss–Kruszka syndrome, a genetic disorder
characterized by neurodevelopmental defects, including autism. Though conserved in …

Cancer cells encounter metabolic stresses such as hypoxia and nutrient limitations because
they grow and divide more quickly than their normal counterparts. In response to glucose …

All-trans retinoic acid (AtRA), an active metabolite of vitamin A, is recognized for its classical
action as an endocrine hormone that triggers genomic effects mediated through nuclear …

Brain inflammation, a common feature in neurodegenerative diseases, is a complex series
of events, which can be detrimental and even lead to neuronal death. Nonetheless, several …