Angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19)

AR Bourgonje, AE Abdulle, W Timens… - The Journal of …, 2020 - Wiley Online Library
Abstract Angiotensin‐converting enzyme 2 (ACE2) has been established as the functional
host receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus …

[HTML][HTML] IL-6: Relevance for immunopathology of SARS-CoV-2

EO Gubernatorova, EA Gorshkova, AI Polinova… - Cytokine & growth factor …, 2020 - Elsevier
COVID-19 mortality is strongly associated with the development of severe pneumonia and
acute respiratory distress syndrome with the worst outcome resulting in cytokine release …

Resolution of coronavirus disease 2019 (COVID-19)

K Habas, C Nganwuchu, F Shahzad… - Expert review of anti …, 2020 - Taylor & Francis
ABSTRACT Introduction Coronavirus disease 2019 (COVID-19) was first detected in China
in December, 2019, and declared as a pandemic by the World Health Organization (WHO) …

[HTML][HTML] Impact of COVID-19 in the mental health in elderly: psychological and biological updates

RE Grolli, MED Mingoti, AG Bertollo, AR Luzardo… - Molecular …, 2021 - Springer
Since December 2019, the world has been experiencing the challenge of facing coronavirus
disease-19 (COVID-19), a severe infectious disease caused by the new coronavirus, SARS …

The interplay between inflammatory pathways and COVID-19: A critical review on pathogenesis and therapeutic options

S Choudhary, K Sharma, O Silakari - Microbial pathogenesis, 2021 - Elsevier
Abstract COVID-19, caused by SARS-CoV-2, emerged as the deadliest outbreak that has
now become a serious health issue to mankind. Activation of inflammatory signaling …

Pain symptoms in patients with coronavirus disease (COVID-19): a literature review

LM Weng, X Su, XQ Wang - Journal of Pain Research, 2021 - Taylor & Francis
Purpose On 11 March, 2020, the coronavirus disease (COVID-19) outbreak was declared as
a global pandemic by the World Health Organization. It brought substantial physical and …

COVID-19 and gastrointestinal disease: implications for the gastroenterologist

RH Hunt, JE East, A Lanas, P Malfertheiner… - Digestive …, 2021 - karger.com
Background: COVID-19 was initially considered a respiratory disease but the SARS-CoV-2
virus can lead to serious systemic consequences affecting major organs including the …

[HTML][HTML] The role of Th17 response in COVID-19

D Martonik, A Parfieniuk-Kowerda, M Rogalska… - Cells, 2021 - mdpi.com
COVID-19 is an acute infectious disease of the respiratory system caused by infection with
the SARS-CoV-2 virus (Severe Acute Respiratory Syndrome Coronavirus 2). Transmission …

Immunological co-ordination between gut and lungs in SARS-CoV-2 infection

S Ahlawat, KK Sharma - Virus research, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into a major
pandemic called coronavirus disease 2019 (COVID-19) that has created unprecedented …

The role of angiotensin converting enzyme 2 in modulating gut microbiota, intestinal inflammation, and coronavirus infection

JM Penninger, MB Grant, JJY Sung - Gastroenterology, 2021 - Elsevier
The role of angiotensin converting enzyme 2 has expanded from regulating the renin
angiotensin system to regulating intestinal amino acid homeostasis and the gut microbiome …