The incidence of inflammatory bowel disease (IBD) has increased in recent years.
Considering the potential side effects of conventional drugs, safe and efficient treatment …

Glycoconjugate vaccines have been effectively used in humans for about 40 years. The
glycoconjugates have substituted plain polysaccharide vaccines that have many limitations …

Polyribosyl-ribitol-phosphate (PRP) from Haemophilus influenzae type b (Hib) is an active
immunizing molecule used in the production of the vaccine against H. influenzae, and …

Bacterial infection remains as one of the major healthcare issues, despite significant
scientific and medical progress in this field. Infection by Streptococcus Pneumoniae (S …

The surface of cells is coated with a dense layer of glycans, known as the cell glycocalyx.
The complex glycans in the glycocalyx are involved in various biological events, such as …

This paper gives an overview of conjugate glycovaccines which contain recombinant
diphtheria toxoid CRM197 as a carrier protein. A special focus is given to synthetic methods …

Bacterial protein glycosylation is commonly mediated by oligosaccharyltransferases
(OTases) that transfer oligosaccharides en bloc from preassembled lipid-linked precursors …

Attenuated Salmonella Typhimurium is a promising antigen delivery system for live vaccines
such as polysaccharides. The length of polysaccharides is a well-known key factor in …

Phosphorylated saccharides are valuable targets in glycochemistry and glycobiology, which
play an important role in various physiological and pathological processes. The current …

Vaccines are essential public health tools and play an important role in reducing the burden
of infectious diseases in the population. Emerging infectious diseases and outbreaks pose …