[HTML][HTML] Improvement of the anticancer efficacy of PD-1/PD-L1 blockade via combination therapy and PD-L1 regulation
M Wu, Q Huang, Y Xie, X Wu, H Ma, Y Zhang… - Journal of hematology & …, 2022 - Springer
Immune checkpoint molecules are promising anticancer targets, among which therapeutic
antibodies targeting the PD-1/PD-L1 pathway have been widely applied to cancer treatment …
antibodies targeting the PD-1/PD-L1 pathway have been widely applied to cancer treatment …
[HTML][HTML] The emerging roles of TRIM21 in coordinating cancer metabolism, immunity and cancer treatment
X Chen, M Cao, P Wang, S Chu, M Li, P Hou… - Frontiers in …, 2022 - frontiersin.org
Tripartite motif containing-21 (TRIM21), an E3 ubiquitin ligase, was initially found to be
involved in antiviral responses and autoimmune diseases. Recently studies have reported …
involved in antiviral responses and autoimmune diseases. Recently studies have reported …
[HTML][HTML] Microfluidic vascular models of tumor cell extravasation
Emerging microfluidic disease models have amply demonstrated their value in many fields
of cancer research. These in vitro technologies recapitulate key aspects of metastatic …
of cancer research. These in vitro technologies recapitulate key aspects of metastatic …
Multicellular 3D bioprinted human gallbladder carcinoma for in vitro mimicry of tumor microenvironment and intratumoral heterogeneity
Y Jin, J Zhang, J Xing, Y Li, H Yang, L Ouyang… - …, 2024 - iopscience.iop.org
Gallbladder carcinoma (GBC) is a malignant hepatobiliary cancer characterized by an
intricate tumor microenvironments (TME) and heterogeneity. The traditional GBC 2D culture …
intricate tumor microenvironments (TME) and heterogeneity. The traditional GBC 2D culture …
[HTML][HTML] Dynamic surveillance of lymphocyte subsets in patients with non-small cell lung cancer during chemotherapy or combination immunotherapy for early …
S Zhen, W Wang, G Qin, T Lu, L Yang… - Frontiers in …, 2024 - frontiersin.org
Background Non-small cell lung cancer (NSCLC) remains the leading cause of cancer-
related deaths worldwide. Lymphocytes are the primary executors of the immune system …
related deaths worldwide. Lymphocytes are the primary executors of the immune system …
Associations of serum cortisol and inflammatory marker features with depression and anxiety in young women with gynecologic cancer
N Qin, S Yi, C Dai, X Liu, Y Duan, Y Zhou, Z Wan… - Supportive Care in …, 2023 - Springer
Purpose Serum cortisol and inflammatory markers may play a role in depression and
anxiety, but little is known about whether various features of serum cortisol and inflammatory …
anxiety, but little is known about whether various features of serum cortisol and inflammatory …
[HTML][HTML] Perturbation of 3D nuclear architecture, epigenomic aging and dysregulation, and cannabinoid synaptopathy reconfigures conceptualization of cannabinoid …
AS Reece, GK Hulse - Frontiers in Psychiatry, 2023 - frontiersin.org
The second part of this paper builds upon and expands the epigenomic-aging perspective
presented in Part 1 to describe the metabolomic and immunomic bases of the epigenomic …
presented in Part 1 to describe the metabolomic and immunomic bases of the epigenomic …