Microglia and other cellular mediators of immunological dysfunction in schizophrenia: a narrative synthesis of clinical findings

KD Nguyen, A Amerio, A Aguglia, L Magnani, A Parise… - Cells, 2023 - mdpi.com
Schizophrenia is a complex psychiatric condition that may involve immune system
dysregulation. Since most putative disease mechanisms in schizophrenia have been …

The Influence of Electroconvulsive Therapy (ECT) on Brain-Derived Neurotrophic Factor (BDNF) Plasma Level in Patients with Schizophrenia—A Systematic Review …

AM Szota, B Kowalewska… - Journal of Clinical …, 2023 - mdpi.com
The main aim of this systematic review and meta-analysis is to establish whether there is a
correlation between the brain-derived neurotrophic factor (BDNF) level and …

[HTML][HTML] Reviewing non-dopaminergic mechanisms for positive and negative schizophrenia symptom management

L Citrome, JM Meyer - The Journal of Clinical Psychiatry, 2023 - psychiatrist.com
Schizophrenia is a chronic and debilitating mental health condition that significantly impacts
quality of life and can shorten patients' lifetime by decades. It is characterized by symptoms …

Discovering functional interactions among schizophrenia-risk genes by combining behavioral genetics with cell biology

D Ma, C Gu - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
Despite much progress in identifying risk genes for polygenic brain disorders, their core
pathogenic mechanisms remain poorly understood. In particular, functions of many proteins …

Hyperactivity and Altered Functional Connectivity of the Ventral Striatum in Schizophrenia Compared with Bipolar Disorder: a resting state fMRI study

L Zhang, W Wang, Y Ruan, Z Li, GJ Ji, Y Tian… - Psychiatry Research …, 2024 - Elsevier
Background Schizophrenia patients frequently present with structural and functional
abnormalities of the ventral striatum (VS). Methods we examined basal activation state and …

Psychosocial and psychological interventions for schizophrenia relapse prevention: A bibliometric analysis

F Liu, W Qiao, X Yuan, G Hei, X Li, Y Zhang… - … Prisms: Global Mental …, 2024 - cambridge.org
Various psychosocial and psychological interventions have been developed to reduce
schizophrenia relapse prevention. A better understanding of these active interventions is …

Association between elevated serum matrix metalloproteinase-2 and tumor necrosis factor-α, and clinical symptoms in male patients with treatment-resistant and …

H Yang, R Peng, M Yang, J Zhang, Z Shi, X Zhang - BMC psychiatry, 2024 - Springer
Background Inflammation has an important role in the pathogenesis of schizophrenia. The
aim of this study was to investigate the levels of tumor necrosis factor (TNF) and matrix …

Meta-analysis of structural and functional brain abnormalities in early-onset schizophrenia

L Wang, R Liu, J Liao, X Xiong, L Xia, W Wang… - Frontiers in …, 2024 - frontiersin.org
Background Previous studies based on resting-state functional magnetic resonance imaging
(rs-fMRI) and voxel-based morphometry (VBM) have demonstrated significant abnormalities …

Decreased serum VEGF and NRG1β1 levels in male patients with chronic schizophrenia: VEGF correlation with clinical symptoms and cognitive deficits

P Chen, W Chen, L Xu, L Luan, R Peng… - Journal of Psychiatric …, 2024 - Elsevier
Background Vascular endothelial growth factor (VEGF) and neuregulin1 (NRG1) are
multifunctional trophic factors reported to be dysregulated in schizophrenia. However, the …

Global Prevalence of Metabolic Syndrome in Schizophrenia Patients: A Systematic Review and Meta-Analysis

N Salari, N Maghami, T Ammari, H Mosafer… - Journal of …, 2024 - Springer
The prevalence of metabolic syndrome in patients with schizophrenia has significantly
increased and can be associated with severe complications such as chronic diseases and …