Cancer is the main cause of death worldwide and metastasis is a major cause of poor
prognosis and cancer-associated mortality. Metastatic conversion of cancer cells is a …

Long non-coding RNAs (lncRNAs) are becoming more prevalent in the cancer field arena,
with functional roles in both oncogenic and onco-suppressive pathways. Despite their …

Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …

Relevance The pathogenesis and biomarkers of ovarian cancer (OC) remain not well-known
in diagnosis, effective therapy, and prognostic assessment in OC personalized medicine …

N6-methyladenosine (m 6 A) is the most common RNA modification and has an important
role in normal development and tumorigenesis. The abnormal expression of m 6 A …

Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal malignancies and rapidly
progressive diseases. Exosomes and long noncoding RNAs (lncRNAs) are emerging as …

Compared to normal cells, cancer cells exhibit specific metabolic characteristics that
facilitate the growth and metastasis of cancer. It is now widely appreciated that long non …

Lung cancer is the most devastating cause of death among all cancers worldwide, and non-
small cell lung cancer (NSCLC) accounts for 80% of all the lung cancer cases. Beyond …

Background Tumor-associated macrophages (TAMs) are a major component of the tumor
microenvironment (TME) and exert an important role in tumor progression. Due to the …

Objectives: Oral squamous cell carcinoma (OSCC) is the most common oral cancer with a
poor prognosis owing to limited understanding of the disease mechanisms. The aim of this …