The term endothelial progenitor cell (EPC) was coined to refer to circulating cells that
displayed the ability to display cell surface antigens similar to endothelial cells in vitro, to …

Circulating bone-marrow-derived cells, named endothelial progenitor cells (EPCs), are
capable of maintaining, generating, and replacing terminally differentiated cells within their …

Neovascularization has been a major challenge in many tissue regeneration strategies.
Hyaluronic acid (HA) of 3–25 disaccharides is known to be angiogenic due to its interaction …

Background Peripheral artery disease (PAD) is associated with a high clinical and
socioeconomic burden. Treatments to alleviate the symptoms of PAD and decrease the risks …

Reactive oxygen species (ROS) are closely related with various pathological disorders.
Therefore, real-time detection of ROS is essential for understanding the procedure of …

Introduction: Angiogenesis is essential to human biology and of great clinical significance.
Excessive or reduced angiogenesis can result in, or exacerbate, several disease states …

Background Poor cell engraftment and survival after transplantation limited the application of
stem cell therapy. Synthetic biomaterials could provide an artificial microenvironment for …

Background: Beyond pharmacological, endovascular and surgical treatment strategies for
peripheral arterial disease (PAD), therapeutic angiogenesis has been advocated to relieve …

Pro-angiogenic therapy provides a promising new perspective in tackling of many common
and severe pathological conditions, such as central and peripheral vascular diseases. Pro …

Methods and Results A total of eight patients (all male, median age 52 years, range 31∼ 77)
with CLI were enrolled in this phase I trial. All patients were considered ineligible for further …