Antimicrobial peptides: mechanism of action, activity and clinical potential

QY Zhang, ZB Yan, YM Meng, XY Hong, G Shao… - Military Medical …, 2021 - Springer
The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …

Polymers as advanced antibacterial and antibiofilm agents for direct and combination therapies

Z Si, W Zheng, D Prananty, J Li, CH Koh, ET Kang… - Chemical …, 2022 - pubs.rsc.org
The growing prevalence of antimicrobial drug resistance in pathogenic bacteria is a critical
threat to global health. Conventional antibiotics still play a crucial role in treating bacterial …

Drug-free antimicrobial nanomotor for precise treatment of multidrug-resistant bacterial infections

L Liu, S Li, K Yang, Z Chen, Q Li, L Zheng, Z Wu… - Nano …, 2023 - ACS Publications
Manufacturing heteronanostructures with specific physicochemical characteristics and tightly
controllable designs is very appealing. Herein, we reported NIR-II light-driven dual …

Antibacterial material surfaces/interfaces for biomedical applications

Y Wang, F Wang, H Zhang, B Yu, H Cong… - Applied Materials Today, 2021 - Elsevier
Biomaterial central infection (BCI) is a tough problem that has attracted high attention. The
most common source of infection in biomaterial centers is bacterial infections. For the past …

[HTML][HTML] Recent advances in the development of metal complexes as antibacterial agents with metal-specific modes of action

JE Waters, L Stevens-Cullinane, L Siebenmann… - Current Opinion in …, 2023 - Elsevier
The mounting burden of antimicrobial resistance (AMR) is one of the most concerning
threats to public health worldwide. With low economic incentives and a dwindling supply of …

Structures and Properties of a Series of High-Spin [CoII2] Complexes Supported by Ancillary Benzoate, Ortho-Hydroxybenzoate, and Para-Hydroxybenzoate …

S Sk, S Biswas, N Dutta, A Das… - Crystal Growth & …, 2023 - ACS Publications
A new series of high-spin [CoII2] complexes [Co2 (cpdp)(μ-O2CC6H5)](1),[Co2 (cpdp)(μ-o-
O2CC6H4 (OH))]· H2O (2), and [Co2 (cpdp)(μ-p-O2CC6H4 (OH))]· 5H2O (3) of the …

Antimicrobial peptides: sustainable application informed by evolutionary constraints

X Chen, J Han, X Cai, S Wang - Biotechnology Advances, 2022 - Elsevier
The proliferation and global expansion of multidrug-resistant (MDR) bacteria have
deepened the need to develop novel antimicrobials. Antimicrobial peptides (AMPs) are …

Expand and Sensitize: Guanidine‐Functionalized Exopolysaccharide Nanoparticles Cause Bacterial Cell Expansion and Antibiotic Sensitization

C Li, HR Jia, F Seidi, X Shi, R Gu, Y Guo… - Advanced Functional …, 2023 - Wiley Online Library
Conventional antibacterial agents and mechanisms are frequently observed to be ineffective
due to the evolution of bacteria to the strains with stronger antibiotic resistance, and hence …

Combating bacterial infections with host defense peptides: Shifting focus from bacteria to host immunity

N Gao, J Wang, C Fang, P Bai, Y Sun, W Wu… - Drug Resistance …, 2023 - Elsevier
The increasing prevalence of multidrug-resistant bacterial infections necessitates the
exploration of novel paradigms for anti-infective therapy. Antimicrobial peptides (AMPs), also …

[HTML][HTML] Mussel-inspired dopamine-CuII coated polyetheretherketone surface with direct and immunomodulatory effect to facilitate osteogenesis, angiogenesis, and …

Z Lyu, Y Zhao, S Huo, F Wang, X Meng, Z Yuan… - Materials & Design, 2022 - Elsevier
Implant-associated infection (IAI) and insufficient implant osseointegration are two primary
concerns of implant failure. Polyetheretherketone (PEEK), though widely used in orthopedic …