The S100 family of proteins contains 25 known members that share a high degree of
sequence and structural similarity. However, only a limited number of family members have …

The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of
intracellular and extracellular functions through regulating calcium balance, cell apoptosis …

Background In order to improve injury assessment of brain injuries, protein markers of
pathophysiological processes and tissue fate have been introduced in the clinic. The most …

The precorneal tear film is a complex mixture of proteins, lipids, metabolites, and electrolytes
with different structures and functionalities. Sustainable production of each tear component …

The Ca2+-binding protein of the EF-hand type, S100B, exerts both intracellular and
extracellular functions. Recent studies have provided more detailed information concerning …

As key players in the host innate immune response, neutrophils are recruited to sites of
infection and constitute the first line of defense. They employ three strategies to eliminate …

Abstract The Receptor for Advanced Glycation Endproducts [RAGE] is an evolutionarily
recent member of the immunoglobulin super-family, encoded in the Class III region of the …

Current information indicates that glial cells participate in all the normal and pathological
processes of the central nervous system. Although much less is known about satellite glial …

Calprotectin (S100A8/A9), a heterodimer of the two calcium-binding proteins S100A8 and
S100A9, was originally discovered as immunogenic protein expressed and secreted by …

The Receptor for Advanced Glycation Endproducts (RAGE) is a multi-ligand receptor of the
immunoglobulin family. RAGE interacts with structurally different ligands probably through …