Climate change and vectorborne diseases

MC Thomson, LR Stanberry - New England Journal of Medicine, 2022 - Mass Medical Soc
Climate Change and Vectorborne Diseases Warming temperatures and changes in
precipitation associated with climate change are affecting the occurrence of vectorborne …

[HTML][HTML] Comparison of Lyme disease in the United States and Europe

AR Marques, F Strle, GP Wormser - Emerging infectious diseases, 2021 - ncbi.nlm.nih.gov
Lyme disease, or Lyme borreliosis, is the most common tickborne disease in the United
States and Europe. In both locations, Ixodes species ticks transmit the Borrelia burgdorferi …

Recent progress in Lyme disease and remaining challenges

JR Bobe, BL Jutras, EJ Horn, ME Embers… - Frontiers in …, 2021 - frontiersin.org
Lyme disease (also known as Lyme borreliosis) is the most common vector-borne disease in
the United States with an estimated 476,000 cases per year. While historically, the long-term …

Development of an mRNA-lipid nanoparticle vaccine against Lyme disease

M Pine, G Arora, TM Hart, E Bettini, BT Gaudette… - Molecular Therapy, 2023 - cell.com
Lyme disease is the most common vector-borne infectious disease in the United States, in
part because a vaccine against it is not currently available for humans. We propose utilizing …

[HTML][HTML] Use of commercial claims data for evaluating trends in Lyme disease diagnoses, United States, 2010–2018

AM Schwartz, KJ Kugeler, CA Nelson… - Emerging infectious …, 2021 - ncbi.nlm.nih.gov
We evaluated MarketScan, a large commercial insurance claims database, for its potential
use as a stable and consistent source of information on Lyme disease diagnoses in the …

The evolving story of Borrelia burgdorferi sensu lato transmission in Europe

A Steinbrink, K Brugger, G Margos, P Kraiczy… - Parasitology …, 2022 - Springer
Beside mosquitoes, ticks are well-known vectors of different human pathogens. In the
Northern Hemisphere, Lyme borreliosis (Eurasia, LB) or Lyme disease (North America, LD) …

Safety and immunogenicity of a novel multivalent OspA-based vaccine candidate against Lyme borreliosis: a randomised, phase 1 study in healthy adults

N Bézay, R Hochreiter, V Kadlecek… - The Lancet Infectious …, 2023 - thelancet.com
Background Lyme borreliosis, potentially associated with serious long-term complications, is
caused by the species complex Borrelia burgdorferi sensu lato. We investigated a novel …

Lyme carditis: from pathophysiology to clinical management

C Radesich, E Del Mestre, K Medo, G Vitrella, P Manca… - Pathogens, 2022 - mdpi.com
Cardiac involvement is a rare but relevant manifestation of Lyme disease that frequently
presents as atrioventricular block (AVB). Immune-mediated injury has been implicated in the …

[HTML][HTML] Economic burden of reported Lyme disease in high-incidence areas, United States, 2014–2016

SA Hook, S Jeon, SA Niesobecki… - Emerging infectious …, 2022 - ncbi.nlm.nih.gov
Approximately 476,000 cases of Lyme disease are diagnosed in the United States annually,
yet comprehensive economic evaluations are lacking. In a prospective study among …

An insecticide target in mechanoreceptor neurons

X Qiao, X Zhang, Z Zhou, L Guo, W Wu, S Ma… - Science …, 2022 - science.org
Hundreds of neurotoxic insecticides are currently in use. However, only a few direct targets
have been identified. Here, using Drosophila and the insecticide flonicamid, we identified …