Rheumatoid arthritis (RA) is considered a chronic systemic, multi-factorial, inflammatory, and
progressive autoimmune disease affecting many people worldwide. While patients show …

Due to the key role of tumor necrosis factor-alpha (TNF-α) in the pathogenesis of
immunoinflammatory diseases, TNF-α inhibitors have been successfully developed and …

Objective Immunogenicity and safety following receipt of the standard SARS–CoV‐2
vaccination regimen in patients with immune‐mediated inflammatory diseases (IMIDs) are …

Tumor Necrosis Factor Inhibitors for Inflammatory Bowel Disease | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Biologic agents have become a core component of therapeutic strategies for many
inflammatory rheumatic diseases. However, perhaps reflecting the specificity and generally …

Biologic drugs have greatly improved treatment outcomes of inflammatory joint diseases, but
a substantial proportion of patients either do not respond to treatment or lose response over …

Objective To evaluate the impact of anti-Tumour Necrosis Factor-α (anti-TNF) treatment on
the occurrence of vasculitic ischaemic events in patients with deficiency of adenosine …

The treatment of patients with axial spondyloarthritis (axSpA) is characterized by non-
pharmacological and pharmacological treatment options. It may depend on the type and …

Abstract Background Anti‐drug antibodies (ADAb) frequently form early in the treatment
course of infliximab and other tumour necrosis factor (TNF) inhibitors, leading to treatment …

Engineered microbes for the delivery of biologics are a promising avenue for the treatment
of various conditions such as chronic inflammatory disorders and metabolic disease. In this …