Tumour necrosis factor inhibitors in inflammatory bowel disease: the story continues

L Peyrin-Biroulet, WJ Sandborn… - Therapeutic …, 2021 - journals.sagepub.com
In the 1990s, tumour necrosis factor-α inhibitor therapy ushered in the biologic therapy era
for inflammatory bowel disease, leading to marked improvements in treatment options and …

Therapeutic protein drug interactions: a white paper from the international consortium for innovation and quality in pharmaceutical development

DE Coutant, DW Boulton, UP Dahal… - Clinical …, 2023 - Wiley Online Library
Typically, therapeutic proteins (TPs) have a low risk for eliciting meaningful drug interactions
(DIs). However, there are select instances where TP drug interactions (TP‐DIs) of clinical …

ECCO topical review: refractory inflammatory bowel disease

T Raine, B Verstockt, U Kopylov… - Journal of Crohn's …, 2021 - academic.oup.com
Inflammatory bowel disease is a chronic disease with variable degrees of extent, severity,
and activity. A proportion of patients will have disease that is refractory to licensed therapies …

Meta‐analysis: persistence of advanced therapies in the treatment of inflammatory bowel disease

TH Yiu, Y Ko, A Pudipeddi, P Natale… - Alimentary …, 2024 - Wiley Online Library
Background The expanding options in advanced therapies for ulcerative colitis (UC) and
Crohn's disease (CD) present challenges in treatment selection. Persistence analysis …

Janus kinase versus TNF inhibitors: where we stand today in rheumatoid arthritis

AI Venetsanopoulou, PV Voulgari… - Expert Review of …, 2022 - Taylor & Francis
ABSTRACT Introduction In recent decades, Rheumatoid arthritis (RA) treatment landscape
has evolved with the induction of new biological and targeted therapies that provide …

[HTML][HTML] Anti-drug antibodies in the biological therapy of autoimmune rheumatic diseases

O Pizano-Martinez, E Mendieta-Condado… - Journal of Clinical …, 2023 - mdpi.com
Autoimmune rheumatic diseases are a cluster of heterogeneous disorders that share some
clinical symptoms such as pain, tissue damage, immune deregulation, and the presence of …

[HTML][HTML] Subcutaneous infliximab monotherapy versus combination therapy with immunosuppressants in inflammatory bowel disease: a post hoc analysis of a …

G D'Haens, W Reinisch, S Schreiber… - Clinical drug …, 2023 - Springer
Abstract Background and Objective Whether benefits and risks of intravenous (IV) infliximab
combotherapy with immunosuppressants versus infliximab monotherapy apply to …

[HTML][HTML] Perspectives on subcutaneous infliximab for rheumatic diseases and inflammatory bowel disease: before, during, and after the COVID-19 era

S Schreiber, S Ben-Horin, R Alten, R Westhovens… - Advances in …, 2022 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic has prompted significant
changes in patient care in rheumatology and gastroenterology, with clinical guidance issued …

[HTML][HTML] Have therapeutics enhanced our knowledge of axial spondyloarthritis?

SR Harrison, H Marzo-Ortega - Current Rheumatology Reports, 2023 - Springer
Abstract Purpose of Review An overview of how the treatment landscape of axial
spondyloarthritis (axSpA) has shaped our understanding of the disease. Recent Findings …

[PDF][PDF] Anthocyanin, tartaric acid, ascorbic acid of roselle flower (Hibiscus sabdariffa L.) for immunomodulatory adjuvant therapy in oral manifestation coronavirus …

NF Ramadhani, AP Nugraha, D Rahmadhani… - J Pharm Pharmacogn …, 2022 - academia.edu
Context: Oral manifestations that arose from COVID-19 infection often causes morbidity and
systemic drug administration is less effective. Roselle flower (Hibiscus sabdariffa) is one of …