When sarcoidosis needs treatment, pharmacotherapy is usually required. Although
glucocorticoids work reliably and relatively quickly for sarcoidosis, these drugs are …

Immune response to biologics treatment, while widely reported, yet fails to correlate with
clinical outcomes and assay to assay comparison is often not possible. Hence, we …

CD4+ T cells contribute to the pathogenesis of autoimmune diseases such as rheumatoid
arthritis (RA). These cells infiltrate the joints of RA patients and produce cytokines, including …

Abstract Background and Objective Juvenile idiopathic arthritis (JIA) is a chronic
autoimmune disorder that primarily affects the joints in children. Notably, it is known to co …

A proof‐of‐concept study with the combination of guselkumab and golimumab in patients
with ulcerative colitis (UC) has shown that the combination therapy resulted in greater …

Behçet's disease is a multi-organ inflammatory disorder with systemic vasculitis of unknown
etiology. Ocular lesions occur in about 70% of patients with Behçet's disease, and it is more …

Background: Immunogenicity to antitumor necrosis factor alpha agents, such as infliximab
(IFX), may lead to therapeutic failure. Objectives: This study evaluated the relationship …

Infliximab and its anti-drug antibody (ADA) serum concentrations exhibit a strong correlation
with clinical response and loss of response. The use of therapeutic drug monitoring to …

Background Hypersensitivity reactions (HSR) to the administration of infliximab (IFX) in
Inflammatory Bowel Diseases (IBD) patients are not rare and usually lead to drug …

Introduction This study aimed to retrospectively examine the drug survival of tumor necrosis
factor (TNF)-alpha inhibitors and switched subsequent biologic agents after discontinuation …