Therapeutic strategies to ameliorate neuronal damage in epilepsy by regulating oxidative stress, mitochondrial dysfunction, and neuroinflammation
S Madireddy, S Madireddy - Brain sciences, 2023 - mdpi.com
Epilepsy is a central nervous system disorder involving spontaneous and recurring seizures
that affects 50 million individuals globally. Because approximately one-third of patients with …
that affects 50 million individuals globally. Because approximately one-third of patients with …
[HTML][HTML] Epilepsy: Mitochondrial connections to the 'Sacred'disease
WH Moos, DV Faller, IP Glavas, I Kanara, K Kodukula… - Mitochondrion, 2023 - Elsevier
Over 65 million people suffer from recurrent, unprovoked seizures. The lack of validated
biomarkers specific for myriad forms of epilepsy makes diagnosis challenging. Diagnosis …
biomarkers specific for myriad forms of epilepsy makes diagnosis challenging. Diagnosis …
The structural connectivity mapping of the intralaminar thalamic nuclei
VJ Kumar, K Scheffler, W Grodd - Scientific Reports, 2023 - nature.com
The intralaminar nuclei of the thalamus play a pivotal role in awareness, conscious
experience, arousal, sleep, vigilance, as well as in cognitive, sensory, and sexual …
experience, arousal, sleep, vigilance, as well as in cognitive, sensory, and sexual …
Mapping hippocampal and thalamic atrophy in epilepsy: A 7‐T magnetic resonance imaging study
Objective Epilepsy patients are often grouped together by clinical variables. Quantitative
neuroimaging metrics can provide a data‐driven alternative for grouping of patients. In this …
neuroimaging metrics can provide a data‐driven alternative for grouping of patients. In this …
Low-frequency stimulation at the subiculum prevents extensive secondary epileptogenesis in temporal lobe epilepsy
Y Shen, Y Gong, X Da, S Gao, S Zhang, M Sun… - Neuroscience …, 2024 - Springer
Secondary epileptogenesis is characterized by increased epileptic susceptibility and a
tendency to generate epileptiform activities outside the primary focus. It is one of the major …
tendency to generate epileptiform activities outside the primary focus. It is one of the major …
The Utility of Responsive Neurostimulation for the Treatment of Pediatric Drug-Resistant Epilepsy
Drug-resistant epilepsy (DRE) has a strongly negative impact on quality of life, as well as the
development of pediatric patients. Surgical treatments have evolved over time, including …
development of pediatric patients. Surgical treatments have evolved over time, including …
[HTML][HTML] Neuronal population representation of human emotional memory
Understanding how emotional processing modulates learning and memory is crucial for the
treatment of neuropsychiatric disorders characterized by emotional memory dysfunction. We …
treatment of neuropsychiatric disorders characterized by emotional memory dysfunction. We …
Predictors of therapeutic response following thalamic neuromodulation for drug‐resistant pediatric epilepsy: A systematic review and individual patient data meta …
We sought to perform a systematic review and individual participant data meta‐analysis to
identify predictors of treatment response following thalamic neuromodulation in pediatric …
identify predictors of treatment response following thalamic neuromodulation in pediatric …
Ventral amygdalofugal pathway as an integrated surgically important network: microsurgical anatomy and segmentation based on fiber dissection
B Erkan, B Hergünsel, O Barut, T Saygı, B Kocak… - Journal of …, 2024 - thejns.org
OBJECTIVE The ventral amygdalofugal pathway (VAFP) provides afferent and efferent
connections to the amygdala and spans along some of the frequently traversed intra-axial …
connections to the amygdala and spans along some of the frequently traversed intra-axial …
Thalamic stereoelectroencephalography for neuromodulation target selection: Proof of concept and review of literature of pulvinar direct electrical stimulation
In patients with drug‐resistant epilepsy (DRE) who are not candidates for resective surgery,
various thalamic nuclei, including the anterior, centromedian, and pulvinar nuclei, have …
various thalamic nuclei, including the anterior, centromedian, and pulvinar nuclei, have …