Bladder cancer stands as a prevalent global malignancy, exhibiting notable sex-based
variations in both incidence and prognosis. Despite substantial strides in therapeutic …

Introduction Cisplatin-based chemotherapy is currently considered the gold-standard
treatment for metastatic urothelial carcinoma (mUC). Nevertheless, most mUC patients …

Chronic myeloid leukemia (CML) is a hematologic malignancy predominantly driven by the
BCR-ABL fusion gene. One of the significant challenges in treating CML lies in the …

Bladder cancer is the 10th most commonly diagnosed cancer with the highest lifetime
treatment costs. The human amniotic membrane (hAM) is the innermost foetal membrane …

Background: Bladder cancer (BLCA) is the most common genitourinary malignancy.
Proliferation essential genes (PEGs) are crucial to the survival of cancer cells. This study …

Background Non-muscle invasive bladder cancer (NMIBC) is one of the most common
malignant tumors of the urinary system. There is an urgent need for further studies to …

Studies have shown that tripartite motif–containing (TRIM) family proteins function as E3
ubiquitin ligases and play essential roles in cancer biology. In the present study, we …

The potential anti-cancer effect of traditional Chinese medicine (TCM) monomers has been
widely studied due to their advantages of well-defined structure, clear therapeutic effects …

Inosine monophosphate dehydrogenase (IMPDH) catalyzes the rate-limiting reaction in the
de novo synthesis pathway of guanine nucleotides that is highly required for cancer cell …

Homoharringtonine (HHT), an alkaloid isolated from Cephalotaxus, is an effective anti-
leukemia agent and exhibits inhibitory effects in various solid tumors. However, the impacts …