Cellular senescence is a biological aging hallmark that plays a key role in the development
of neurodegenerative diseases. Clinical trials are currently underway to evaluate the …

Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID
(LC) are characterized by similar immunological alterations, persistence of chronic viral …

Hyperbaric oxygen therapy (HBOT) is the clinical application of oxygen at pressures higher
than atmospheric pressure. HBOT has been effectively used to manage diverse clinical …

Oxygen is a powerful trigger for cellular reactions, but there are few comparative
investigations assessing the effects over a large range of partial pressures. We investigated …

Abstract Hyperbaric oxygen therapy (HBOT), a technique through which 100% oxygen is
provided at a pressure higher than 1 atm absolute (ATA), has become a well-established …

By addressing the mechanisms involved in transcription, signaling, stress reaction,
apoptosis and cell-death, cellular structure and cell-to-cell contacts, adhesion, migration as …

Chronic wounds have always been considered as “gordian knots” in medicine, in which
hypoxia plays a key role in blocking healing. To address this challenge, although tissue …

Background: Diabetes mellitus is one of the most common metabolic diseases. The most
serious complication of diabetes is diabetic foot ulcer, which affects several million people …

Ischemic stroke (IS) has become the second leading cause of morbidity and mortality
worldwide, and the prevention of IS should be given high priority. Recent studies have …

Background For decades, the basic treatment strategies of necrotizing soft tissue infections
(NSTI) have remained unchanged, primarily relying on aggressive surgical removal of …