[HTML][HTML] Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety

MA Hannan, MA Rahman, AAM Sohag, MJ Uddin… - Nutrients, 2021 - mdpi.com
Mounting evidence support the potential benefits of functional foods or nutraceuticals for
human health and diseases. Black cumin (Nigella sativa L.), a highly valued nutraceutical …

[HTML][HTML] The role of medicinal and aromatic plants against obesity and arthritis: A review

AK Paul, R Jahan, A Paul, T Mahboob, TA Bondhon… - Nutrients, 2022 - mdpi.com
Obesity is a significant health concern, as it causes a massive cascade of chronic
inflammations and multiple morbidities. Rheumatoid arthritis and osteoarthritis are chronic …

Anti‐arthritic effect of chicken embryo tissue hydrolyzate against adjuvant arthritis in rats (X‐ray microtomographic and histopathological analysis)

I Rzhepakovsky, S Anusha Siddiqui… - Food Science & …, 2021 - Wiley Online Library
Finding new, safe strategies to prevent and control rheumatoid arthritis is an urgent task.
Bioactive peptides and peptide‐rich protein hydrolyzate represent a new trend in the …

Activation of the Nrf2/HO-1 signaling pathway by dimethyl fumarate ameliorates complete Freund's adjuvant-induced arthritis in rats

R Lal, J Dhaliwal, N Dhaliwal, RN Dharavath… - European Journal of …, 2021 - Elsevier
The nuclear factor erythroid 2-related factor (Nrf2) signaling pathway has recently emerged
as a novel therapeutic target in treating various diseases. Therefore, the present study …

[HTML][HTML] Nigella sativa's anti-inflammatory and antioxidative effects in experimental inflammation

RM Pop, O Sabin, Ș Suciu, SC Vesa, SA Socaci… - Antioxidants, 2020 - mdpi.com
Nigella sativa (NS) has been used for centuries in various inflammatory conditions because
of its anti-inflammatory and antioxidant activities. The study aimed to evaluate the anti …

Evaluation of antiarthritic and antinociceptive effects of cedrol in a rat model of arthritis

F Forouzanfar, AM Pourbagher-Shahri… - … Medicine and Cellular …, 2022 - Wiley Online Library
Pharmacological studies revealed that cedrol, a natural sesquiterpene, has antioxidant, anti‐
inflammatory, and analgesic properties. This study is aimed at evaluating the potential …

[HTML][HTML] Black Cumin Seed (Nigella sativa) in Inflammatory Disorders: Therapeutic Potential and Promising Molecular Mechanisms

HK Rashwan, S Mahgoub, NZ Abuelezz… - Drugs and Drug …, 2023 - mdpi.com
Inflammation is an essential defense mechanism against harmful stimuli. However,
uncontrolled inflammatory mechanisms culminate in disturbed responses that contribute to …

Identification of bioactive components on antihemorrhoidal activity of Cistus laurifolius L. using RP-HPLC and LC-QTOF-MS

S Pekacar, B Özüpek, EK Akkol, H Taştan… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Cistus laurifolius is widely used in folk medicine in
Anatolia for the treatment of many ailments. The leaves of the plant are used in the form of …

8-Shogaol inhibits rheumatoid arthritis through targeting TAK1

S Jo, S Samarpita, JS Lee, YJ Lee, JE Son… - Pharmacological …, 2022 - Elsevier
Rheumatoid arthritis (RA) is a chronic immune-mediated disorder, mainly characterized by
synovial inflammation and joint damage. If insufficiently treated, RA can lead to irreversible …

[HTML][HTML] The effect of dietary supplementation with Nigella sativa (black seeds) mediates immunological function in male Wistar rats

HS Mahmoud, AA Almallah, HN Gad EL-Hak… - Scientific reports, 2021 - nature.com
This experiment aimed to investigate the effect of dietary Nigella sativa on the cell-mediated
immune response. Eighteen male Wistar rats were divided equally into a control group and …