[HTML][HTML] Resting-state connectivity in neurodegenerative disorders: Is there potential for an imaging biomarker?

C Hohenfeld, CJ Werner, K Reetz - NeuroImage: Clinical, 2018 - Elsevier
Biomarkers in whichever modality are tremendously important in diagnosing of disease,
tracking disease progression and clinical trials. This applies in particular for disorders with a …

Linking the cerebellum to Parkinson disease: an update

T Li, W Le, J Jankovic - Nature Reviews Neurology, 2023 - nature.com
Parkinson disease (PD) is characterized by heterogeneous motor and non-motor symptoms,
resulting from neurodegeneration involving various parts of the central nervous system …

[HTML][HTML] Noradrenergic and cholinergic systems take centre stage in neuropsychiatric diseases of ageing

IF Orlando, JM Shine, TW Robbins, JB Rowe… - Neuroscience & …, 2023 - Elsevier
Noradrenergic and cholinergic systems are among the most vulnerable brain systems in
neuropsychiatric diseases of ageing, including Alzheimer's disease, Parkinson's disease …

Cerebellar atrophy in neurodegeneration—a meta-analysis

HM Gellersen, CC Guo, C O'Callaghan… - Journal of Neurology …, 2017 - jnnp.bmj.com
Introduction The cerebellum has strong cortical and subcortical connectivity, but is rarely
taken into account for clinical diagnosis in many neurodegenerative conditions, particularly …

Flexible brain dynamics underpins complex behaviours as observed in Parkinson's disease

P Sorrentino, R Rucco, F Baselice, R De Micco… - Scientific reports, 2021 - nature.com
Rapid reconfigurations of brain activity support efficient neuronal communication and
flexible behaviour. Suboptimal brain dynamics is associated to impaired adaptability …

Neuroprotective effects of curcumin on the cerebellum in a rotenone‐induced Parkinson's disease Model

H Fikry, LA Saleh… - CNS Neuroscience & …, 2022 - Wiley Online Library
Aims Parkinson's disease (PD) is the second most prevalent age‐related neurodegenerative
disorder. The cerebellum plays a role in PD pathogenesis. Curcumin has numerous …

Machine learning for detecting parkinson's disease by resting-state functional magnetic resonance imaging: A multicenter radiomics analysis

D Shi, H Zhang, G Wang, S Wang, X Yao… - Frontiers in aging …, 2022 - frontiersin.org
Parkinson's disease (PD) is one of the most common progressive degenerative diseases,
and its diagnosis is challenging on clinical grounds. Clinically, effective and quantifiable …

Cerebro-cerebellar motor networks in clinical subtypes of Parkinson's disease

S Basaia, F Agosta, A Francia, C Cividini… - npj Parkinson's …, 2022 - nature.com
Parkinson's disease (PD) patients can be classified in tremor-dominant (TD) and postural-
instability-and-gait-disorder (PIGD) motor subtypes. PIGD represents a more aggressive …

Basal ganglia atrophy–associated causal structural network degeneration in Parkinson's disease

R Li, T Zou, X Wang, H Wang, X Hu, F Xie… - Human brain …, 2022 - Wiley Online Library
Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by both
motor and non‐motor symptoms. A convergent pathophysiological hallmark of PD is an early …

Hippocampal atrophy and intrinsic brain network dysfunction relate to alterations in mind wandering in neurodegeneration

C O'Callaghan, JM Shine, JR Hodges… - Proceedings of the …, 2019 - National Acad Sciences
Mind wandering represents the human capacity for internally focused thought and relies
upon the brain's default network and its interactions with attentional networks. Studies have …