Diabetes mellitus is a heterogeneous chronic metabolic disorder characterized by the
presence of hyperglycemia, commonly preceded by a prediabetic state. The excess of blood …

With the acceleration of population aging, nervous system diseases including Alzheimer's
disease (AD), Parkinson's disease (PD), Huntington's disease (HD), anxiety, depression …

Background Cataracts are the main cause of reversible blindness worldwide. The ageing of
the lens caused by ultraviolet B (UVB) radiation is mostly related to oxidative stress (OS) …

Hydrogen sulfide (H2S) is an endogenous biologically active gas produced in mammalian
tissues. It plays a very critical role in many pathophysiological processes in the body. It can …

Sorafenib is a tyrosine kinase inhibitor that shows anti-tumour effects against various
cancers including gastric cancer (GC). However, the clinical application of sorafenib is often …

Injuries of the central (CNS) and peripheral nervous system (PNS) are a serious problem of
the modern healthcare system. The situation is complicated by the lack of clinically effective …

Ferroptosis is an iron-dependent regulated form of cell death caused by excessive lipid
peroxidation. This form of cell death differed from known forms of cell death in morphological …

Objective. Glucocorticoid‐induced osteonecrosis of the femoral head is one of the most
common causes of nontraumatic osteonecrosis of the femoral head, but its exact …

Hydrostatic pressure, stretch, and shear are major biomechanical forces of vessels and play
critical roles in genesis and development of hypertension. Our previous work demonstrated …

Iron plays an essential role in various physiological processes. A disruption in iron
homeostasis can lead to severe consequences, including impaired neurodevelopment …