Young-onset colorectal cancer

MCW Spaander, AG Zauber, S Syngal… - Nature reviews Disease …, 2023 - nature.com
In the past decades the incidence of colorectal cancer (CRC) in people under the age of 50
years has increased, which is referred to as early-onset CRC or young-onset CRC (YO …

The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection

SG Patel, JJ Karlitz, T Yen, CH Lieu… - The lancet …, 2022 - thelancet.com
The incidence of early-onset colorectal—ie, colorectal cancer cancer diagnosed in patients
under the age of 50 years—has been increasing around the world. This Series paper …

[HTML][HTML] Delphi initiative for early-onset colorectal cancer (DIRECt) international management guidelines

GM Cavestro, A Mannucci, F Balaguer… - Clinical …, 2023 - Elsevier
Background & Aims Patients with early-onset colorectal cancer (eoCRC) are managed
according to guidelines that are not age-specific. A multidisciplinary international group …

[HTML][HTML] Epidemiology and biology of early onset colorectal cancer

A Venugopal, JM Carethers - EXCLI journal, 2022 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third leading cause of cancer-related mortality in men or
women in the United States. Average-risk screening that begins at age 50 years has …

Changing epidemiology of colorectal cancer—birth cohort effects and emerging risk factors

CC Murphy, TA Zaki - Nature reviews Gastroenterology & hepatology, 2024 - nature.com
Incidence and mortality of colorectal cancer (CRC) are increasing worldwide, suggesting
broad changes in the epidemiology of CRC. In this Review, we discuss the changes that are …

The role of diet and lifestyle in early-onset colorectal cancer: a systematic review

M Puzzono, A Mannucci, S Grannò, RA Zuppardo… - Cancers, 2021 - mdpi.com
Simple Summary This systematic review sifted through the exogenous dietary and lifestyle
risk factors associated with early-onset colorectal cancer, going through the putative …

[HTML][HTML] Association of diabetes mellitus with early-onset colorectal cancer: a systematic review and meta-analysis of 19 studies including 10 million individuals and …

HDK Ta, NN Nguyen, DKN Ho, HD Nguyen… - Diabetes & Metabolic …, 2023 - Elsevier
Background and aims Early-onset colorectal cancer (EoCRC) constitutes 2%–10% of all
colorectal cancers and is becoming more common globally. Diabetes mellitus (DM) has …

Time to diagnosis and treatment in younger adults with colorectal cancer: A systematic review

M Castelo, C Sue-Chue-Lam, L Paszat, T Kishibe… - Plos one, 2022 - journals.plos.org
Background The incidence of colorectal cancer is rising in adults< 50 years of age. As a
primarily unscreened population, they may have clinically important delays to diagnosis and …

[HTML][HTML] Risk of colorectal cancer in patients with irritable bowel syndrome: a meta-analysis of population-based observational studies

X Wu, J Wang, Z Ye, J Wang, X Liao, M Liv… - Frontiers in …, 2022 - frontiersin.org
Background and Aims: Evidence on the association between irritable bowel syndrome (IBS)
and colorectal cancer (CRC) risk is inconsistent. Therefore, we aimed to examine whether …

People with early-onset colorectal cancer describe primary care barriers to timely diagnosis: a mixed-methods study of web-based patient reports in the United …

K Lamprell, DF Pulido, G Arnolda, BNG Easpaig… - BMC Primary …, 2023 - Springer
Background People with early-onset colorectal cancer, under the age of 50, are more likely
to experience diagnostic delay and to be diagnosed at later stages of the disease than older …