Cancer stem cells: advances in knowledge and implications for cancer therapy
X Chu, W Tian, J Ning, G Xiao, Y Zhou… - … and Targeted Therapy, 2024 - nature.com
Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …
Nanomaterials for mRNA‐based therapeutics: Challenges and opportunities
D Li, Q Liu, M Yang, H Xu, M Zhu… - Bioengineering & …, 2023 - Wiley Online Library
Messenger RNA (mRNA) holds great potential in developing immunotherapy, protein
replacement, and genome editing. In general, mRNA does not have the risk of being …
replacement, and genome editing. In general, mRNA does not have the risk of being …
Cancer stem cells and the tumor microenvironment: targeting the critical crosstalk through nanocarrier systems
A Nayak, NM Warrier, P Kumar - Stem cell reviews and reports, 2022 - Springer
The physiological state of the tumor microenvironment (TME) plays a central role in cancer
development due to multiple universal features that transcend heterogeneity and niche …
development due to multiple universal features that transcend heterogeneity and niche …
Insights on development aspects of polymeric nanocarriers: the translation from bench to clinic
AK Tewari, SC Upadhyay, M Kumar, K Pathak… - Polymers, 2022 - mdpi.com
Scientists are focusing immense attention on polymeric nanocarriers as a prominent delivery
vehicle for several biomedical applications including diagnosis of diseases, delivery of …
vehicle for several biomedical applications including diagnosis of diseases, delivery of …
Dendrimer: An update on recent developments and future opportunities for the brain tumors diagnosis and treatment
A brain tumor is an uncontrolled cell proliferation, a mass of tissue composed of cells that
grow and divide abnormally and appear to be uncontrollable by the processes that normally …
grow and divide abnormally and appear to be uncontrollable by the processes that normally …
Dendrimer-mediated delivery of DNA and RNA vaccines
LA Kisakova, EK Apartsin, LF Nizolenko, LI Karpenko - Pharmaceutics, 2023 - mdpi.com
DNA and RNA vaccines (nucleic acid-based vaccines) are a promising platform for vaccine
development. The first mRNA vaccines (Moderna and Pfizer/BioNTech) were approved in …
development. The first mRNA vaccines (Moderna and Pfizer/BioNTech) were approved in …
The Spicy Science of Dendrimers in the Realm of Cancer Nanomedicine: A Report from the COST Action CA17140 Nano2Clinic
S Pricl - Pharmaceutics, 2023 - mdpi.com
COST Action CA17140 Cancer Nanomedicine—from the bench to the bedside
(Nano2Clinic,) is the first, pan-European interdisciplinary network of representatives from …
(Nano2Clinic,) is the first, pan-European interdisciplinary network of representatives from …
Effects of cationic dendrimers and their complexes with microRNAs on immunocompetent cells
N Knauer, E Pashkina, A Aktanova, O Boeva… - Pharmaceutics, 2022 - mdpi.com
Short regulatory oligonucleotides are considered prospective tools for immunotherapy.
However, they require an adequate carrier to deliver potential therapeutics into immune …
However, they require an adequate carrier to deliver potential therapeutics into immune …
Polyethylenimine, an Autophagy-Inducing Platinum-Carbene-Based Drug Carrier with Potent Toxicity towards Glioblastoma Cancer Stem Cells
C McCartin, C Dussouillez, C Bernhard, E Mathieu… - Cancers, 2022 - mdpi.com
Simple Summary The resistance of tumours to treatment and their tendency to reoccur
following successful treatment are major problems for long-term cancer patient survival …
following successful treatment are major problems for long-term cancer patient survival …
Effects of Dendrimer-microRNA Nanoformulations against Glioblastoma Stem Cells
N Knauer, M Meschaninova, S Muhammad, D Hänggi… - Pharmaceutics, 2023 - mdpi.com
Glioblastoma is a rapidly progressing tumor quite resistant to conventional treatment. These
features are currently assigned to a self-sustaining population of glioblastoma stem cells …
features are currently assigned to a self-sustaining population of glioblastoma stem cells …