The essential role of primary cilia in cerebral cortical development and disorders

S Liu, MX Trupiano, J Simon, J Guo… - Current topics in …, 2021 - Elsevier
Primary cilium, first described in the 19th century in different cell types and organisms by
Alexander Ecker, Albert Kolliker, Aleksandr Kowalevsky, Paul Langerhans, and Karl …

[HTML][HTML] Beyond neuronal microtubule stabilization: MAP6 and CRMPS, two converging stories

C Cuveillier, B Boulan, C Ravanello… - Frontiers in Molecular …, 2021 - frontiersin.org
The development and function of the central nervous system rely on the microtubule (MT)
and actin cytoskeletons and their respective effectors. Although the structural role of the …

[HTML][HTML] TTBK2 and primary cilia are essential for the connectivity and survival of cerebellar Purkinje neurons

E Bowie, SC Goetz - Elife, 2020 - elifesciences.org
Primary cilia are vital signaling organelles that extend from most types of cells, including
neurons and glia. These structures are essential for development of many tissues and …

[图书][B] The clinical neuroscience of lateralization

A Mundorf, S Ocklenburg - 2021 - taylorfrancis.com
The Clinical Neuroscience of Lateralization gives the first comprehensive transdiagnostic
overview of the evidence for changes in hemispheric asymmetries in different psychiatric …

[HTML][HTML] The DNA methylome in panic disorder: a case-control and longitudinal psychotherapy-epigenetic study

C Ziegler, F Grundner-Culemann, MA Schiele… - Translational …, 2019 - nature.com
In panic disorder (PD), epigenetic mechanisms such as DNA methylation of candidate
genes have been suggested to play a key role at the intersection of genetic and …

Patterns of cilia gene dysregulations in major psychiatric disorders

W Alhassen, S Chen, M Vawter, BK Robbins… - Progress in Neuro …, 2021 - Elsevier
Primary cilia function as cells' antennas to detect and transduce external stimuli and play
crucial roles in cell signaling and communication. The vast majority of cilia genes that are …

[HTML][HTML] Lasting and sex-dependent impact of maternal immune activation on molecular pathways of the amygdala

MR Keever, P Zhang, CR Bolt, AM Antonson… - Frontiers in …, 2020 - frontiersin.org
The prolonged and sex-dependent impact of maternal immune activation (MIA) during
gestation on the molecular pathways of the amygdala, a brain region that influences social …

[HTML][HTML] Primary cilia dysfunction in neurodevelopmental disorders beyond ciliopathies

V Karalis, KE Donovan, M Sahin - Journal of Developmental Biology, 2022 - mdpi.com
Primary cilia are specialized, microtubule-based structures projecting from the surface of
most mammalian cells. These organelles are thought to primarily act as signaling hubs and …

To beat, or not to beat, that is question! The spectrum of ciliopathies

C Kempeneers, MA Chilvers - Pediatric Pulmonology, 2018 - Wiley Online Library
Cilia are widely distributed throughout the human body, and have numerous roles in
physiology, development, and disease. Ciliary ultrastructure is complex, consisting of nine …

[HTML][HTML] Limitations and opportunities in the pharmacotherapy of ciliopathies

MD Phu, S Bross, MD Burkhalter, M Philipp - Pharmacology & Therapeutics, 2021 - Elsevier
Ciliopathies are a family of rather diverse conditions, which have been grouped based on
the finding of altered or dysfunctional cilia, potentially motile, small cellular antennae …