Hypomethylating agents and chemotherapy in MDS

L Adès, V Santini - Best Practice & Research Clinical Haematology, 2013 - Elsevier
Until recently, the treatment of higher risk myelodysplastic syndrome was based on [1]
Intensive chemotherapy using anthracycline–AraC combinations, leading to a lower …

[PDF][PDF] The role of stem cell source in autologous hematopoietic stem cell transplantation for patients with myelodysplastic syndromes.

TJM de Witte, R Brand, A Biezen, M Delforge… - 2006 - repository.ubn.ru.nl
BACKGROUND AND OBJECTIVES: Intensive chemotherapy followed by autologous
hematopoietic stem cell transplantation (HSCT) is a curative treatment option for patients …

Efficacy and toxicity of decitabine versus CHG regimen (low-dose cytarabine, homoharringtonine and granulocyte colony-stimulating factor) in patients with higher risk …

L Wu, X Li, C Chang, F Xu, Q He, D Wu… - Leukemia & …, 2016 - Taylor & Francis
Decitabine and CHG regimen (low-dose cytarabine and homoharringtonine with G-CSF)
have been used for treating higher risk myelodysplastic syndrome (MDS). In this study, we …

The bridge treatment selected at the decision for transplantation did not affect the outcomes in patients with MDS

S Kako, Y Kanda, J Kato, W Yamamoto… - Hematological …, 2017 - Wiley Online Library
The optimal treatment for use as a bridge to allogeneic hematopoietic stem cell
transplantation at the decision for transplantation has not been established in patients with …

Reduced-intensity conditioning followed by allogeneic hematopoietic cell transplantation in myeloid diseases

U Platzbecker, G Ehninger, N Schmitz… - Annals of …, 2003 - Springer
Within the past years, reduced or modified doses of chemotherapy or radiotherapy have
been widely studied for conditioning before allogeneic hematopoietic cell transplantation in …

Allogeneic hematopoietic cell transplantation in patients with myelodysplastic syndromes

U Platzbecker - Seminars in hematology, 2012 - Elsevier
Despite new developments in innovative and potentially targeted drugs like hypomethylating
agents (HMA), allogeneic hematopoietic stem cell transplantation (HCT) is still the only …

Stem Cell Transplantationfor Leukemias Following Myelodysplastic Syndromesor Secondaryto Cytotoxic Therapy

T Witte, M Oosterveld, B Span, P Muus… - Reviews in Clinical …, 2002 - Wiley Online Library
Two main forms of therapy‐related myelodysplastic syndrome and acute myeloid leukemia (t‐
MDS/AML) have been recognized. The most frequent type, occurring after treatment with …

[HTML][HTML] Hematopoietic stem cell transplantation for myelodysplastic syndrome

S Parmar, M de Lima - Biology of Blood and Marrow Transplantation, 2010 - Elsevier
Allogeneic hematopoietic stem cell transplantation remains the only curative option for
myelodysplastic syndrome, but patients with this disease are often older and frail, and …

Hematopoietic cell transplantation for myelodysplastic syndrome

HJ Deeg - American Society of Clinical Oncology Educational …, 2015 - ascopubs.org
Although high-dose chemotherapy may cure a small subset of patients with myelodysplastic
syndrome (MDS), allogeneic hematopoietic cell transplantation (HCT) is the only currently …

Autologous stem cell transplantation in myelodysplastic syndromes

T De Witte, S Suciu, R Brand, P Muus, N Kröger - Seminars in hematology, 2007 - Elsevier
Allogeneic stem cell transplantation (SCT) is the treatment of choice for the majority of young
patients with myelodysplasia (MDS) who have a histocompatible donor (sibling or unrelated …