Methods of tissue decellularization used for preparation of biologic scaffolds and in vivo relevance

TJ Keane, IT Swinehart, SF Badylak - Methods, 2015 - Elsevier
Biologic scaffolds composed of extracellular matrix (ECM) are widely used in both preclinical
animal studies and in many clinical applications to repair and reconstruct tissues. Recently …

Collagen—emerging collagen based therapies hit the patient

EA Abou Neel, L Bozec, JC Knowles, O Syed… - Advanced drug delivery …, 2013 - Elsevier
The choice of biomaterials available for regenerative medicine continues to grow rapidly,
with new materials often claiming advantages over the short-comings of those already in …

Extracellular matrix-based biomaterials and their influence upon cell behavior

MC Cramer, SF Badylak - Annals of biomedical engineering, 2020 - Springer
Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix (ECM)
are commonly used for the repair and remodeling of injured tissue. The clinical outcomes …

The extracellular matrix as a scaffold for tissue reconstruction

SF Badylak - Seminars in cell & developmental biology, 2002 - Elsevier
The extracellular matrix (ECM) consists of a complex mixture of structural and functional
proteins and serves an important role in tissue and organ morphogenesis, maintenance of …

[HTML][HTML] Sterilization and disinfection methods for decellularized matrix materials: Review, consideration and proposal

M Tao, T Ao, X Mao, X Yan, R Javed, W Hou, Y Wang… - Bioactive materials, 2021 - Elsevier
Sterilization is the process of killing all microorganisms, while disinfection is the process of
killing or removing all kinds of pathogenic microorganisms except bacterial spores …

Decellularized ECM hydrogels: prior use considerations, applications, and opportunities in tissue engineering and biofabrication

J Kort-Mascort, S Flores-Torres, O Peza-Chavez… - Biomaterials …, 2023 - pubs.rsc.org
Tissue development, wound healing, pathogenesis, regeneration, and homeostasis rely
upon coordinated and dynamic spatial and temporal remodeling of extracellular matrix …

Naturally occurring scaffolds for soft tissue repair and regeneration

J Hodde - Tissue engineering, 2002 - liebertpub.com
Cell growth supports (ie, scaffolds) that provide a conducive environment for normal cellular
growth, differentiation, and angiogenesis are important components of tissue engineered …

Development and characterisation of a full-thickness acellular porcine bladder matrix for tissue engineering

F Bolland, S Korossis, SP Wilshaw, E Ingham, J Fisher… - Biomaterials, 2007 - Elsevier
The aim of this study was to produce a natural, acellular matrix from porcine bladder tissue
for use as a scaffold in developing a tissue-engineered bladder replacement. Full-thickness …

Human extracellular matrix (ECM) powders for injectable cell delivery and adipose tissue engineering

JS Choi, HJ Yang, BS Kim, JD Kim, JY Kim… - Journal of Controlled …, 2009 - Elsevier
Here, we present extracellular matrix (ECM) powders derived from human adipose tissue as
injectable cell delivery carriers for adipose tissue engineering. We postulate that human …

[HTML][HTML] Marrow-derived cells populate scaffolds composed of xenogeneic extracellular matrix

SF Badylak, K Park, N Peppas, G McCabe… - Experimental …, 2001 - Elsevier
INTRODUCTION: The source of cells that participate in wound repair directly affects
outcome. The extracellular matrix (ECM) and other acellular biomaterials have been used as …