The identification of agents that can reverse drug resistance in cancer chemotherapy, and
enhance the overall efficacy is of great interest. Paclitaxel (PTX) belongs to taxane family …

To concurrently suppress multidrug resistance (MDR) and metastasis of breast cancer cells,
paclitaxel (PTX) and honokiol (HNK) were coencapsulated into pH-sensitive polymeric …

Background MicroRNAs (miRNAs) play crucial roles in the development of hepatocellular
carcinoma (HCC). Hsa-microRNA-27b-3p (hsa-miR-27b) is involved in the formation and …

Ovarian cancer accounts for the major part of the mortality attributable to female reproductive
system malignant tumors worldwide. Recently, the incidence of ovarian cancer has been …

Background/Aim: Periprostatic adipose tissue (PPAT) directs tumour behaviour.
Microenvironment secretome provides information related to its biology. This study was …

Transforming growth factor-β-activated kinase 1 (TAK1)-binding protein 3 (TAB3) and the
proviral integration site for Moloney murine leukaemia virus 1 (PIM1) are implicated in …

An altered microRNA (miRNA/miR)‑27a‑3p expression has been identified in cervical
cancer, while the exact regulatory mechanisms responsible for the dysregulation of miR‑27a …

Objective The objective of this research was to determine the age cut-off for worse prognosis
and investigate age-related differentially expressed genes (DEGs) in patients with advanced …

Recurrence within 6 months of the last round of chemotherapy is clinically defined as
platinum-resistant ovarian cancer. Gene expression associated with early recurrence may …

Acute pancreatitis (AP) is a clinically common inflammatory disease, NF-κB activation and
the secretion of pro-inflammatory mediators have been considered as the main events of AP …