The beta cell-immune cell interface in type 1 diabetes (T1d)
EA James, AV Joglekar, AK Linnemann, HA Russ… - Molecular …, 2023 - Elsevier
Background T1D is an autoimmune disease in which pancreatic islets of Langerhans are
infiltrated by immune cells resulting in the specific destruction of insulin-producing islet beta …
infiltrated by immune cells resulting in the specific destruction of insulin-producing islet beta …
Role of interferons in the antiviral battle: from virus-host crosstalk to prophylactic and therapeutic potential in SARS-CoV-2 infection
Mammalians sense antigenic messages from infectious agents that penetrate the respiratory
and digestive epithelium, as well as signals from damaged host cells through membrane …
and digestive epithelium, as well as signals from damaged host cells through membrane …
Associations of gut microbiota alterations with clinical, metabolic, and immune-inflammatory characteristics of chronic schizophrenia
B Misiak, E Pawlak, K Rembacz, M Kotas… - Journal of Psychiatric …, 2024 - Elsevier
The present study had the following aims: 1) to compare gut microbiota composition in
patients with schizophrenia and controls and 2) to investigate the association of differentially …
patients with schizophrenia and controls and 2) to investigate the association of differentially …
[HTML][HTML] SOCS-JAK-STAT inhibitors and SOCS mimetics as treatment options for autoimmune uveitis, psoriasis, lupus, and autoimmune encephalitis
R Pandey, M Bakay, H Hakonarson - Frontiers in Immunology, 2023 - frontiersin.org
Autoimmune diseases arise from atypical immune responses that attack self-tissue epitopes,
and their development is intricately connected to the disruption of the JAK-STAT signaling …
and their development is intricately connected to the disruption of the JAK-STAT signaling …
Macrophages treated with interferons induce different responses in lymphocytes via extracellular vesicles
F Giannessi, Z Percario, V Lombardi, A Sabatini… - Iscience, 2024 - cell.com
Limited information exists regarding the impact of interferons (IFNs) on the information
carried by extracellular vesicles (EVs). This study aimed at investigating whether IFN-α2b …
carried by extracellular vesicles (EVs). This study aimed at investigating whether IFN-α2b …
T Cell Response in Tuberculosis-Infected Patients Vaccinated against COVID-19
LHA Cavalcante-Silva, EG Leite, FS Almeida… - Microorganisms, 2023 - mdpi.com
Many studies have focused on SARS-CoV-2 and Mycobacterium tuberculosis (Mtb) co-
infection consequences. However, after a vaccination plan against COVID-19, the cases of …
infection consequences. However, after a vaccination plan against COVID-19, the cases of …
Varicella‐zoster virus‐related neurological complications: From infection to immunomodulatory therapies
MA Hakami, FR Khan, O Abdulaziz… - Reviews in Medical …, 2024 - Wiley Online Library
The Varicella‐zoster virus (VZV), classified as a neurotropic member of the Herpesviridae
family, exhibits a characteristic pathogenicity, predominantly inducing varicella, commonly …
family, exhibits a characteristic pathogenicity, predominantly inducing varicella, commonly …
Verapamil and tangeretin enhances the M1 macrophages to M2 type in lipopolysaccharide-treated mice and inhibits the P-glycoprotein expression by downregulating …
A Kundu, P Ghosh, B Bishayi - International Immunopharmacology, 2024 - Elsevier
LPS induced sepsis is a complex process involving various immune cells and signaling
molecules. Dysregulation of macrophage polarization and ROS production contributed to …
molecules. Dysregulation of macrophage polarization and ROS production contributed to …
The potential role of interleukins and interferons in ovarian cancer
Ovarian cancer poses significant challenges and remains a highly lethal disease with limited
treatment options. In the context of ovarian cancer, interleukins (ILs) and interferons (IFNs) …
treatment options. In the context of ovarian cancer, interleukins (ILs) and interferons (IFNs) …
Interferons prime the endothelium for toll-like receptor–mediated thrombin generation
KD Sack, N Eaton, MD Tehrani… - Journal of Thrombosis and …, 2024 - Elsevier
Background Respiratory infection is associated with microvascular thrombus formation and
marked elevation in cytokine levels. The role of cytokines elaborated by the pulmonary …
marked elevation in cytokine levels. The role of cytokines elaborated by the pulmonary …