Aging is a complex biological process accompanied by a progressive decline in the physical
function of the organism and an increased risk of age-related chronic diseases such as …

Sarcopenia is a progressive skeletal muscle disease that occurs most commonly in the
elderly population, contributing to increased costs and hospitalization. Exercise and …

Muscle atrophy and sarcopenia (the term given to the age-related decline in muscle mass
and function), influence an individuals risk of falls, frailty, functional decline, and, ultimately …

The rapid increase in both the lifespan and proportion of older adults is accompanied by the
unprecedented rise in age-associated chronic diseases, including sarcopenia and obesity …

Sarcopenia, featured by the progressive loss of skeletal muscle function and mass, is
associated with the impaired function of muscle stem cells (MuSCs) caused by increasing …

The human genome is capable of producing hundreds of thousands of different proteins and
non‐coding RNAs from< 20 000 genes, in a co‐ordinated and regulated fashion. This is …

Insight on the underlying mechanisms of aging will advance our ability to extend healthspan,
treat age-related pathology and improve quality of life. Multiple genetic and pharmacological …

Background: Sarcopenia is associated with poor clinical outcomes in patients with locally
advanced gastric cancer (LAGC). Currently, the diagnostic criteria for sarcopenia are …

Major hallmarks of functional loss, loss of metabolic and musculoskeletal health and (multi)
morbidity with aging are associated with sleep disturbances. With poor sleep shifts in gut …

Cellular senescence may be associated with morphological changes in skeletal muscle and
changes in physical function with age although there have been few human studies. We …