Review of recent developments in GC–MS approaches to metabolomics-based research

DJ Beale, FR Pinu, KA Kouremenos, MM Poojary… - Metabolomics, 2018 - Springer
Background Metabolomics aims to identify the changes in endogenous metabolites of
biological systems in response to intrinsic and extrinsic factors. This is accomplished …

[HTML][HTML] Application of metabolomics in Alzheimer's disease

JM Wilkins, E Trushina - Frontiers in neurology, 2018 - frontiersin.org
Progress toward the development of efficacious therapies for Alzheimer's disease (AD) is
halted by a lack of understanding early underlying pathological mechanisms. Systems …

Metabolomics in cancer biomarker discovery: current trends and future perspectives

EG Armitage, C Barbas - Journal of pharmaceutical and biomedical …, 2014 - Elsevier
Cancer is one of the most devastating human diseases that causes a vast number of
mortalities worldwide each year. Cancer research is one of the largest fields in the life …

Omics technologies in allergy and asthma research: An EAACI position paper

U Radzikowska, K Baerenfaller, JA Cornejo‐Garcia… - Allergy, 2022 - Wiley Online Library
Allergic diseases and asthma are heterogenous chronic inflammatory conditions with
several distinct complex endotypes. Both environmental and genetic factors can influence …

[HTML][HTML] Diet-induced metabolic changes of the human gut microbiome: importance of short-chain fatty acids, methylamines and indoles

MBH Abdul Rahim, J Chilloux, L Martinez-Gili… - Acta …, 2019 - Springer
The human gut is a home for more than 100 trillion bacteria, far more than all other microbial
populations resident on the body's surface. The human gut microbiome is considered as a …

Breathomics for the clinician: the use of volatile organic compounds in respiratory diseases

W Ibrahim, L Carr, R Cordell, MJ Wilde, D Salman… - Thorax, 2021 - thorax.bmj.com
Exhaled breath analysis has the potential to provide valuable insight on the status of various
metabolic pathways taking place in the lungs locally and other vital organs, via systemic …

Metabolomics: definitions and significance in systems biology

A Klassen, AT Faccio, GAB Canuto… - … : from fundamentals to …, 2017 - Springer
Nowadays, there is a growing interest in deeply understanding biological mechanisms not
only at the molecular level (biological components) but also the effects of an ongoing …

The application of ion mobility mass spectrometry to metabolomics

X Zhang, K Quinn, C Cruickshank-Quinn… - Current Opinion in …, 2018 - Elsevier
Highlights•Advantages/limitations of IMMS for metabolomics are reviewed.•IMMS can offer
improved compound identification and metabolome coverage.•Commercial IMMS systems …

Nontargeted metabolomic analysis to unravel the impact of di (2-ethylhexyl) phthalate stress on root exudates of alfalfa (Medicago sativa)

Y Wang, W Ren, Y Li, Y Xu, Y Teng, P Christie… - Science of the total …, 2019 - Elsevier
Root exudates are the main media of information communication and energy transfer
between plant roots and the soil. Understanding the response of root exudates to …

Combined genomic, transcriptomic, and metabolomic analyses provide insights into chayote (Sechium edule) evolution and fruit development

A Fu, Q Wang, J Mu, L Ma, C Wen, X Zhao… - Horticulture …, 2021 - academic.oup.com
Chayote (Sechium edule) is an agricultural crop in the Cucurbitaceae family that is rich in
bioactive components. To enhance genetic research on chayote, we used Nanopore third …