The role of nucleoid‐associated proteins in the organization and compaction of bacterial chromatin

RT Dame - Molecular microbiology, 2005 - Wiley Online Library
The bacterial chromosomal DNA is folded into a compact structure called nucleoid. The
shape and size of this 'body'is determined by a number of factors. Major players are DNA …

Regulation of gene expression by histone-like proteins in bacteria

CJ Dorman, P Deighan - Current opinion in genetics & development, 2003 - Elsevier
Histone-like proteins in bacteria contribute to the control of gene expression, as well as
participating in other DNA transactions such as recombination and DNA replication. They …

The shape of the DNA minor groove directs binding by the DNA-bending protein Fis

S Stella, D Cascio, RC Johnson - Genes & development, 2010 - genesdev.cshlp.org
The bacterial nucleoid-associated protein Fis regulates diverse reactions by bending DNA
and through DNA-dependent interactions with other control proteins and enzymes. In …

Genome-wide analysis of Fis binding in Escherichia coli indicates a causative role for A-/AT-tracts

BK Cho, EM Knight, CL Barrett, BØ Palsson - Genome research, 2008 - genome.cshlp.org
We determined the genome-wide distribution of the nucleoid-associated protein Fis in
Escherichia coli using chromatin immunoprecipitation coupled with high-resolution whole …

Anatomy of Escherichia coli σ 70 promoters

RK Shultzaberger, Z Chen, KA Lewis… - Nucleic acids …, 2007 - academic.oup.com
Abstract Information theory was used to build a promoter model that accounts for the− 10,
the− 35 and the uncertainty of the gap between them on a common scale. Helical face …

Concentration-dependent exchange accelerates turnover of proteins bound to double-stranded DNA

JS Graham, RC Johnson, JF Marko - Nucleic acids research, 2011 - academic.oup.com
The multistep kinetics through which DNA-binding proteins bind their targets are heavily
studied, but relatively little attention has been paid to proteins leaving the double helix …

Targeted and random bacterial gene disruption using a group II intron (targetron) vector containing a retrotransposition‐activated selectable marker

J Zhong, M Karberg, AM Lambowitz - Nucleic acids research, 2003 - academic.oup.com
Mobile group II introns have been used to develop a novel class of gene targeting vectors,
targetrons, which employ base pairing for DNA target recognition and can thus be …

An architectural role of the Escherichia coli chromatin protein FIS in organising DNA

R Schneider, R Lurz, G Lüder, C Tolksdorf… - Nucleic acids …, 2001 - academic.oup.com
The Escherichia coli chromatin protein FIS modulates the topology of DNA in a growth
phase-dependent manner. In this study we have investigated the global effect of FIS binding …

Alterations to the expression level of mitochondrial transcription factor A, TFAM, modify the mode of mitochondrial DNA replication in cultured human cells

JLO Pohjoismäki, S Wanrooij… - Nucleic acids …, 2006 - academic.oup.com
Mitochondrial transcription factor A (TFAM) is an abundant mitochondrial protein of the HMG
superfamily, with various putative roles in mitochondrial DNA (mtDNA) metabolism. In this …

Mechanism of chromosome compaction and looping by the Escherichia coli nucleoid protein Fis

D Skoko, D Yoo, H Bai, B Schnurr, J Yan… - Journal of molecular …, 2006 - Elsevier
Fis, the most abundant DNA-binding protein in Escherichia coli during rapid growth, has
been suspected to play an important role in defining nucleoid structure. Using bulk-phase …