Cancer-derived exosomes: their role in cancer biology and biomarker development

VC Kok, CC Yu - International Journal of Nanomedicine, 2020 - Taylor & Francis
Exosomes are a subset of tiny extracellular vesicles manufactured by all cells and are
present in all body fluids. They are produced actively in tumor cells, which are released and …

Circulating microRNAs in cancer: potential and challenge

M Cui, H Wang, X Yao, D Zhang, Y Xie, R Cui… - Frontiers in …, 2019 - frontiersin.org
MicroRNAs (miRNAs) are endogenous non-coding small RNA molecules that can be
secreted into the circulation and exist in remarkably stable forms. Like intercellular miRNAs …

circRNA-miRNA-mRNA in breast cancer

M Zhang, X Bai, X Zeng, J Liu, F Liu, Z Zhang - Clinica Chimica Acta, 2021 - Elsevier
Among cancers, breast cancer has the highest incidence rate among women and poses a
tremendous threat to women's health. Messenger RNA (mRNA), microRNA (miRNA) and …

Exosomal miR-1910-3p promotes proliferation, metastasis, and autophagy of breast cancer cells by targeting MTMR3 and activating the NF-κB signaling pathway

B Wang, J Mao, B Wang, L Wang, H Wen, L Xu, J Fu… - Cancer letters, 2020 - Elsevier
Exosomes are key mediators of intercellular communication and play a role in the
pathogenesis and progression of cancer. Exosomes in circulating body fluids serve as …

Hypoxia, endoplasmic reticulum stress and chemoresistance: dangerous liaisons

M Akman, DC Belisario, IC Salaroglio… - Journal of Experimental …, 2021 - Springer
Solid tumors often grow in a micro-environment characterized by< 2% O 2 tension. This
condition, together with the aberrant activation of specific oncogenic patwhays, increases …

An electrochemical biosensor for simultaneous detection of breast cancer clinically related microRNAs based on a gold nanoparticles/graphene quantum dots …

C Pothipor, J Jakmunee, S Bamrungsap, K Ounnunkad - Analyst, 2021 - pubs.rsc.org
A label-free multiplexed electrochemical biosensor based on a gold nanoparticles/graphene
quantum dots/graphene oxide (AuNPs/GQDs/GO) modified three-screen-printed carbon …

Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion

L Huang, L Zhang, X Chen - Briefings in Bioinformatics, 2022 - academic.oup.com
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

Recent progresses in DNA nanostructure-based biosensors for detection of tumor markers

R Huang, N He, Z Li - Biosensors and Bioelectronics, 2018 - Elsevier
DNA has emerged as a promising biomaterial for assembling a variety of nanostructures
based on its programmable base pairing. It also has other remarkable properties including …

Novel quinazoline-based EGFR kinase inhibitors: A review focussing on SAR and molecular docking studies (2015-2019)

P Bhatia, V Sharma, O Alam, A Manaithiya… - European Journal of …, 2020 - Elsevier
The over expression of EGFR has been recognized as the driver mechanism in the
occurrence and progression of carcinomas such as lung cancer, breast cancer, pancreatic …

The role of exosomal microRNAs in the tumor microenvironment of breast cancer

Q Liu, F Peng, J Chen - International journal of molecular sciences, 2019 - mdpi.com
Breast cancer, ranking first among women's cancers worldwide, develops from the breast
tissue. Study of the breast tissue is, therefore of great significance to the diagnosis and …