Electronic cigarette harms: Aggregate evidence shows damage to biological systems

SL Hamann, N Kungskulniti, N Charoenca… - International Journal of …, 2023 - mdpi.com
Evidence of the harms of e-cigarettes has been unfolding slowly and has been documented
in many reviews and reports worldwide. A narrative review of new evidence is presented …

Nicotine: from discovery to biological effects

L Sansone, F Milani, R Fabrizi, M Belli… - International Journal of …, 2023 - mdpi.com
Nicotine, the primary psychoactive agent in tobacco leaves, has led to the widespread use of
tobacco, with over one billion smokers globally. This article provides a historical overview of …

Smoking cessation and short-and longer-term mortality

ER Cho, IK Brill, IT Gram, PE Brown, P Jha - NEJM evidence, 2024 - evidence.nejm.org
Background Smoking cessation reduces mortality and morbidity. However, the extent and
rapidity at which cessation reduces contemporary death rates from smoking-related …

Impact of the gut microbiome on nicotine's motivational effects and glial cells in the ventral tegmental area in male mice

A Lakosa, A Rahimian, F Tomasi, F Marti… - …, 2023 - nature.com
A link between gut dysbiosis and the pathogenesis of brain disorders has been identified. A
role for gut bacteria in drug reward and addiction has been suggested but very few studies …

Cigarette smoke induces epithelial-to-mesenchymal transition, stemness, and metastasis in lung adenocarcinoma cells via upregulated RUNX-2/galectin-3 pathway

JR Sharma, H Agraval, UCS Yadav - Life Sciences, 2023 - Elsevier
Aims An elevated level of galectin-3, a carbohydrate-binding lectin implicated in
tumorigenesis, metastasis, and epithelial-mesenchymal transition (EMT), has been found in …

[HTML][HTML] Electronic nicotine delivery system: end to smoking or just a new fancy cigarette

SS Kotewar, A Pakhale, R Tiwari, A Reche, SR Singi - Cureus, 2023 - ncbi.nlm.nih.gov
Smoking and tobacco chewing are the predominant causes of oral cancer. Tobacco is the
second-most widely consumed psychoactive substance. There are numerous ways to quit …

[HTML][HTML] JWA inhibits nicotine-induced lung cancer stemness and progression through CHRNA5/AKT-mediated JWA/SP1/CD44 axis

K Ding, X Jiang, J Ni, C Zhang, A Li, J Zhou - … and Environmental Safety, 2023 - Elsevier
Cigarette smoking is an independent risk factor for lung cancer. Nicotine, as an addictive
substance in tobacco and e-cigarettes, is known to promote tumor progression and …

[HTML][HTML] Efficacy of insula deep repetitive transcranial magnetic stimulation combined with varenicline for smoking cessation: a randomized, double-blind, sham …

C Ibrahim, VM Tang, DM Blumberger, S Malik… - Brain Stimulation, 2023 - Elsevier
Background Current smoking cessation treatments are limited in terms of efficacy,
particularly with regards to long term abstinence. There is a large amount of evidence …

Mechanisms of E-Cigarette Vape-Induced Epithelial Cell Damage

E Auschwitz, J Almeda, CD Andl - Cells, 2023 - mdpi.com
E-cigarette use has been reported to affect cell viability, induce DNA damage, and modulate
an inflammatory response resulting in negative health consequences. Most studies focus on …

Bio-psycho-social factors' associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants

M Korbmacher, TP Gurholt, AMG de Lange… - Frontiers in …, 2023 - frontiersin.org
Brain age refers to age predicted by brain features. Brain age has previously been
associated with various health and disease outcomes and suggested as a potential …