Development and functions of the choroid plexus–cerebrospinal fluid system
The choroid plexus (ChP) is the principal source of cerebrospinal fluid (CSF), which has
accepted roles as a fluid cushion and a sink for nervous system waste in vertebrates …
accepted roles as a fluid cushion and a sink for nervous system waste in vertebrates …
The role of neurod genes in brain development, function, and disease
S Tutukova, V Tarabykin… - Frontiers in Molecular …, 2021 - frontiersin.org
Transcriptional regulation is essential for the correct functioning of cells during development
and in postnatal life. The basic Helix-loop-Helix (bHLH) superfamily of transcription factors is …
and in postnatal life. The basic Helix-loop-Helix (bHLH) superfamily of transcription factors is …
[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …
types with specific spatial distribution patterns and structural and functional properties …
Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays
Spatially resolved transcriptomic technologies are promising tools to study complex
biological processes such as mammalian embryogenesis. However, the imbalance between …
biological processes such as mammalian embryogenesis. However, the imbalance between …
A single-cell transcriptome atlas profiles early organogenesis in human embryos
The early window of human embryogenesis is largely a black box for developmental
biologists. Here we probed the cellular diversity of 4–6 week human embryos when …
biologists. Here we probed the cellular diversity of 4–6 week human embryos when …
K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas
Abstract Canonical (H3. 1/H3. 2) and noncanonical (H3. 3) histone 3 K27M-mutant gliomas
have unique spatiotemporal distributions, partner alterations and molecular profiles. The …
have unique spatiotemporal distributions, partner alterations and molecular profiles. The …
Self-organizing models of human trunk organogenesis recapitulate spinal cord and spine co-morphogenesis
S Gribaudo, R Robert, B van Sambeek, C Mirdass… - Nature …, 2023 - nature.com
Integrated in vitro models of human organogenesis are needed to elucidate the multi-
systemic events underlying development and disease. Here we report the generation of …
systemic events underlying development and disease. Here we report the generation of …
[图书][B] The evolution of the sensitive soul: Learning and the origins of consciousness
S Ginsburg, E Jablonka - 2019 - books.google.com
A new theory about the origins of consciousness that finds learning to be the driving force in
the evolutionary transition to basic consciousness. What marked the evolutionary transition …
the evolutionary transition to basic consciousness. What marked the evolutionary transition …
Self-organizing 3D human trunk neuromuscular organoids
JMF Martins, C Fischer, A Urzi, R Vidal, S Kunz… - Cell stem cell, 2020 - cell.com
Neuromuscular networks assemble during early human embryonic development and are
essential for the control of body movement. Previous neuromuscular junction modeling …
essential for the control of body movement. Previous neuromuscular junction modeling …
[PDF][PDF] Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord
The coordinated spatial and temporal regulation of gene expression in the vertebrate neural
tube determines the identity of neural progenitors and the function and physiology of the …
tube determines the identity of neural progenitors and the function and physiology of the …