2DE: the phoenix of proteomics
BM Oliveira, JR Coorssen, D Martins-de-Souza - Journal of proteomics, 2014 - Elsevier
Given the rapid developments in mass spectrometry (MS) in terms of sensitivity, mass
accuracy, and throughput, some have suggested that two-dimensional gel electrophoresis …
accuracy, and throughput, some have suggested that two-dimensional gel electrophoresis …
Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia
D Martins-de-Souza, G Maccarrone, T Wobrock… - Journal of psychiatric …, 2010 - Elsevier
Schizophrenia (SCZ) is the result of DNA alterations and environmental factors, which
together lead to differential protein expression and ultimately to the development of the …
together lead to differential protein expression and ultimately to the development of the …
Proteomic approaches to unravel the complexity of schizophrenia
D Martins-de-Souza, PC Guest… - Expert Review of …, 2012 - Taylor & Francis
Schizophrenia is a debilitating mental disorder that affects approximately 30 million people
worldwide. The development and progression of this disease is now thought to be …
worldwide. The development and progression of this disease is now thought to be …
Different apolipoprotein E, apolipoprotein A1 and prostaglandin-H2 D-isomerase levels in cerebrospinal fluid of schizophrenia patients and healthy controls
D Martins-De-Souza, T Wobrock, I Zerr… - The World Journal of …, 2010 - Taylor & Francis
Objectives. To identify proteins differentially expressed in schizophrenia patients, we
collected 50 µl cerebrospinal fluid from 17 first-episode schizophrenia patients and 10 …
collected 50 µl cerebrospinal fluid from 17 first-episode schizophrenia patients and 10 …
[HTML][HTML] Isobaric Tagging-Based Quantification for Proteomic Analysis: A Comparative Study of Spared and Affected Muscles from mdx Mice at the Early Phase of …
CY Matsumura, B Menezes de Oliveira, M Durbeej… - PloS one, 2013 - journals.plos.org
Duchenne muscular dystrophy (DMD) is the most common childhood myopathy,
characterized by muscle loss and cardiorespiratory failure. While the genetic basis of DMD …
characterized by muscle loss and cardiorespiratory failure. While the genetic basis of DMD …
[HTML][HTML] Quantitative proteomic analysis reveals metabolic alterations, calcium dysregulation, and increased expression of extracellular matrix proteins in laminin α2 …
BM de Oliveira, CY Matsumura… - Molecular & Cellular …, 2014 - ASBMB
Congenital muscular dystrophy with laminin α2 chain deficiency (MDC1A) is one of the most
severe forms of muscular disease and is characterized by severe muscle weakness and …
severe forms of muscular disease and is characterized by severe muscle weakness and …
Identification of differentially displayed proteins in cerebrospinal fluid of Parkinson's disease patients: a proteomic approach
BACKGROUND: Clinical proteomics has been widely used to identify differentially displayed
proteins in blood and cerebrospinal fluid (CSF) to understand the molecular and cellular …
proteins in blood and cerebrospinal fluid (CSF) to understand the molecular and cellular …
Plant proteomics and systems biology
FV Winck, ALW Dos Santos… - Advances in Plant Omics …, 2022 - Springer
Proteome analysis of model and non-model plants is a genuine scientific field in expansion.
Several technological advances have contributed to the implementation of different …
Several technological advances have contributed to the implementation of different …
[HTML][HTML] Shotgun mass spectrometry workflow combining IEF and LC-MALDI-TOF/TOF
G Maccarrone, CW Turck, D Martins-de-Souza - The protein journal, 2010 - Springer
We present a high throughput shotgun mass spectrometry workflow using a bidimensional
peptide fractionation procedure consisting of isoelectric focusing and RP-HPLC prior to …
peptide fractionation procedure consisting of isoelectric focusing and RP-HPLC prior to …
[HTML][HTML] Proteomic analysis during larval development and metamorphosis of the spionid polychaete Pseudopolydora vexillosa
FSY Mok, V Thiyagarajan, PY Qian - Proteome Science, 2009 - Springer
Background While the larval-juvenile transition (metamorphosis) in the spionid polychaete
Pseudopolydora vexillosa involves gradual morphological changes and does not require …
Pseudopolydora vexillosa involves gradual morphological changes and does not require …