This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …

Off-target effects of systemically administered drugs have been a major hurdle in designing
therapies with desired efficacy and acceptable toxicity. Developing targeting strategies to …

Molecularly imprinted polymers (MIPs) are tailor-made chemical receptors that recognize
and bind target molecules with a high affinity and selectivity. MIPs came into the spotlight in …

Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …

The immunosuppressive tumor microenvironment (TME) represents a major barrier for
effective immunotherapy. Tumor-associated macrophages (TAMs) are highly heterogeneous …

Prodrugs are molecules with little or no pharmacological activity that are converted to the
active parent drug in vivo by enzymatic or chemical reactions or by a combination of the two …

Folates have a pterine core structure and high metabolic activity due to their ability to accept
electrons and react with O-, S-, N-, C-bounds. Folates play a role as cofactors in essential …

The increasing prevalence of cancer, a disease in which rapid and uncontrollable cell
growth causes complication and tissue dysfunction, is one of the serious and tense concerns …

Despite the enormous therapeutic potential of immune checkpoint blockade (ICB), it benefits
only a small subset of patients. Some chemotherapeutics can switch 'immune-cold'tumours …