Ligand-targeted drug delivery

M Srinivasarao, PS Low - Chemical reviews, 2017 - ACS Publications
Safety and efficacy constitute the major criteria governing regulatory approval of any new
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …

Versatile types of organic/inorganic nanohybrids: from strategic design to biomedical applications

N Zhao, L Yan, X Zhao, X Chen, A Li, D Zheng… - Chemical …, 2018 - ACS Publications
Organic/inorganic nanohybrids have attracted widespread interests due to their favorable
properties and promising applications in biomedical areas. Great efforts have been made to …

Advanced photosensitizer activation strategies for smarter photodynamic therapy beacons

BM Luby, CD Walsh, G Zheng - … Chemie International Edition, 2019 - Wiley Online Library
Photodynamic therapy (PDT) is a clinical treatment in which a light‐absorbing drug called a
photosensitizer (PS) is combined with light and molecular oxygen to generate cytotoxic …

The delivery of therapeutic oligonucleotides

RL Juliano - Nucleic acids research, 2016 - academic.oup.com
The oligonucleotide therapeutics field has seen remarkable progress over the last few years
with the approval of the first antisense drug and with promising developments in late stage …

[HTML][HTML] Surface functionalization and targeting strategies of liposomes in solid tumor therapy: A review

MK Riaz, MA Riaz, X Zhang, C Lin, KH Wong… - International journal of …, 2018 - mdpi.com
Surface functionalization of liposomes can play a key role in overcoming the current
limitations of nanocarriers to treat solid tumors, ie, biological barriers and physiological …

Iron oxide based nanoparticles for multimodal imaging and magnetoresponsive therapy

N Lee, D Yoo, D Ling, MH Cho, T Hyeon… - Chemical …, 2015 - ACS Publications
Magnetic nanoparticles have received tremendous attention in diverse fields because of
their unique nanoscale physicochemical properties and the potential for a wide range of …

X-ray-activated nanosystems for theranostic applications

X Chen, J Song, X Chen, H Yang - Chemical Society Reviews, 2019 - pubs.rsc.org
X-rays are widely applied in clinical medical facilities for radiotherapy (RT) and biomedical
imaging. However, the sole use of X-rays for cancer treatment leads to insufficient radiation …

Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

VP Torchilin - Nature reviews Drug discovery, 2014 - nature.com
The use of nanoparticulate pharmaceutical drug delivery systems (NDDSs) to enhance the
in vivo effectiveness of drugs is now well established. The development of multifunctional …

[HTML][HTML] Fluorescence-guided surgery

T Nagaya, YA Nakamura, PL Choyke… - Frontiers in …, 2017 - frontiersin.org
Surgical resection of cancer remains an important treatment modality. Despite advances in
preoperative imaging, surgery itself is primarily guided by the surgeon's ability to locate …

Heteroatom-doped carbon dots: synthesis, characterization, properties, photoluminescence mechanism and biological applications

Q Xu, T Kuang, Y Liu, L Cai, X Peng… - Journal of Materials …, 2016 - pubs.rsc.org
Heteroatom-doped carbon dots (CDs), due to their excellent photoluminescence (PL)
properties, attracted widespread attention recently and demonstrated immense promise for …