Rare-earth up-converting nanophosphors (UCNPs) have great potential to become a new
generation of biological luminescent labels, but their use has been limited by difficulties in …

We present the first direct comparative evaluation of an antibody–drug conjugate and of a
small molecule–drug conjugate for cancer therapy, using chemically defined products which …

Cancer is one of the major causes of death worldwide and its treatment remains very
challenging. The effectiveness of cancer therapy significantly depends upon tumour-specific …

The potential of poly (2-oxazoline) or POZ to be a versatile and broad based platform for
drug delivery with wide utility in multiple therapeutic areas has long been recognized by …

Starving therapy based on tumor calcification has been considered as a promising strategy
with high biosafety for tumor treatment. However, the limited calcium (Ca2+) concentration …

A multifunctional diagnosis and treatment integration platform is crucial in cancer treatments.
Here, we show that by integrating Gd-doped silicon nanoparticles (Si–Gd NPs), chlorine e6 …

Hypoxia, one of the representative characteristics in solid tumors, not only reduces the
effectiveness of multiple treatments, but also relates to the tumor invasion and metastasis …

Chemotherapy is widely applied to treat cancer patients but its application is limited due to
the systemic toxicity and low efficacy. Nanocarrier system, which is capable of delivering …

Superparamagnetic iron oxides possess specific magnetic properties in the presence of an
external magnetic field, which make them an attractive platform as contrast agents for …

Folate receptors are up-regulated on a variety of human cancers, including cancers of the
breast, ovaries, endometrium, lungs, kidneys, colon, brain, and myeloid cells of …