Fabrication of fluorescent nanoparticles based on AIE luminogens (AIE dots) and their applications in bioimaging

S Chen, H Wang, Y Hong, BZ Tang - Materials Horizons, 2016 - pubs.rsc.org
Fluorescent nanoparticles (NPs) represent a new group of contrast agents for bioimaging.
One of the challenging problems in this area is to fabricate fluorescent NPs with improved …

Dual targeted immunotherapy via in vivo delivery of biohybrid RNAi‐peptide nanoparticles to tumor‐associated macrophages and cancer cells

J Conde, C Bao, Y Tan, D Cui… - Advanced functional …, 2015 - Wiley Online Library
Lung cancer is associated with very poor prognosis and considered one of the leading
causes of death worldwide. Here, highly potent and selective biohybrid RNA interference …

Targeted magnetic iron oxide nanoparticles for tumor imaging and therapy

XH Peng, X Qian, H Mao, AY Wang… - International journal …, 2008 - Taylor & Francis
Magnetic iron oxide (IO) nanoparticles with a long blood retention time, biodegradability and
low toxicity have emerged as one of the primary nanomaterials for biomedical applications …

Urinary bladder cancer in dogs, a naturally occurring model for cancer biology and drug development

DW Knapp, JA Ramos-Vara, GE Moore… - ILAR …, 2014 - academic.oup.com
Each year more than 65,000 people are diagnosed with urinary bladder cancer, and more
than 14,000 people die from the disease in the United States. Studies in relevant animal …

Medical applications of organic–inorganic hybrid materials within the field of silica-based bioceramics

M Vallet-Regí, M Colilla, B González - Chemical society reviews, 2011 - pubs.rsc.org
Research on bioceramics has evolved from the use of inert materials for mere substitution of
living tissues towards the development of third-generation bioceramics aimed at inducing …

Quantum-dot-tagged reduced graphene oxide nanocomposites for bright fluorescence bioimaging and photothermal therapy monitored in situ

SH Hu, YW Chen, WT Hung, IW Chen… - Advanced …, 2012 - ir.lib.nycu.edu.tw
Quantum-dot-tagged reduced graphene oxide (QD-rGO) nanocomposites (left) internalized
into targeted tumor cells display bright fluorescence from the QDs (right); by absorbing NIR …

[HTML][HTML] Direct in vivo evidence of activated macrophages in human osteoarthritis

VB Kraus, G McDaniel, JL Huebner, TV Stabler… - Osteoarthritis and …, 2016 - Elsevier
Objective Through binding to folate receptor-β (FR-β), the new 99m Tc–EC20 (Etarfolatide)
imaging technique detects activated but not resting macrophages in vivo. The goal of this …

Near-infrared fluorescence imaging in immunotherapy

Y Ji, C Jones, Y Baek, GK Park, S Kashiwagi… - Advanced drug delivery …, 2020 - Elsevier
Near-infrared (NIR) light possesses many suitable optophysical properties for medical
imaging including low autofluorescence, deep tissue penetration, and minimal light …

A unique matched quadruplet of terbium radioisotopes for PET and SPECT and for α-and β−-radionuclide therapy: an in vivo proof-of-concept study with a new …

C Müller, K Zhernosekov, U Köster… - Journal of nuclear …, 2012 - Soc Nuclear Med
Terbium offers 4 clinically interesting radioisotopes with complementary physical decay
characteristics: 149Tb, 152Tb, 155Tb, and 161Tb. The identical chemical characteristics of …

Bioceramics for drug delivery

D Arcos, M Vallet-Regi - Acta Materialia, 2013 - Elsevier
Bioceramics, such as calcium phosphate ceramics and cements and silica-based glasses,
are widely used as components of implants for bone and teeth restoration. Nowadays, the …