Near-Infrared Fluorescent Probe Activated by Nitroreductase for In Vitro and In Vivo Hypoxic Tumor Detection
Tumor hypoxia is correlated with increased resistance to chemotherapy and poor overall
prognoses across a number of cancer types. We present here a cancer cell-selective and …
prognoses across a number of cancer types. We present here a cancer cell-selective and …
[HTML][HTML] Soy lecithin-derived liposomal delivery systems: Surface modification and current applications
NTT Le, VD Cao, TNQ Nguyen, TTH Le… - International journal of …, 2019 - mdpi.com
The development of natural phospholipids for nanostructured drug delivery systems has
attracted much attention in the past decades. Lecithin that was derived from naturally …
attracted much attention in the past decades. Lecithin that was derived from naturally …
Antibody–drug conjugates and small molecule–drug conjugates: opportunities and challenges for the development of selective anticancer cytotoxic agents …
G Casi, D Neri - Journal of medicinal chemistry, 2015 - ACS Publications
Conventional cancer chemotherapy heavily relies on the use of cytotoxic agents, which
typically do not preferentially localize at the tumor site and cause toxicity to normal organs …
typically do not preferentially localize at the tumor site and cause toxicity to normal organs …
Synthesis, characterization, and in vivo targeted imaging of amine-functionalized rare-earth up-converting nanophosphors
Rare-earth up-converting nanophosphors (UCNPs) have great potential to become a new
generation of biological luminescent labels, but their use has been limited by difficulties in …
generation of biological luminescent labels, but their use has been limited by difficulties in …
[HTML][HTML] Inflammatory biomarkers in osteoarthritis
HN Daghestani, VB Kraus - Osteoarthritis and cartilage, 2015 - Elsevier
Osteoarthritis (OA) is highly prevalent and a leading cause of disability worldwide. Despite
the global burden of OA, diagnostic tests and treatments for the molecular or early …
the global burden of OA, diagnostic tests and treatments for the molecular or early …
[HTML][HTML] Targeted nanomaterials for phototherapy
U Chitgupi, Y Qin, JF Lovell - Nanotheranostics, 2017 - ncbi.nlm.nih.gov
Phototherapies involve the irradiation of target tissues with light. To further enhance
selectivity and potency, numerous molecularly targeted photosensitizers and photoactive …
selectivity and potency, numerous molecularly targeted photosensitizers and photoactive …
[HTML][HTML] Doxorubicin-Loaded Core–Shell UiO-66@SiO2 Metal–Organic Frameworks for Targeted Cellular Uptake and Cancer Treatment
DB Trushina, AY Sapach, OA Burachevskaia… - Pharmaceutics, 2022 - mdpi.com
Beneficial features of biocompatible high-capacity UiO-66 nanoparticles, mesoporous SiO2,
and folate-conjugated pluronic F127 were combined to prepare the core–shell UiO-66 …
and folate-conjugated pluronic F127 were combined to prepare the core–shell UiO-66 …
Core-shell structured nanoparticles for photodynamic therapy-based cancer treatment and related imaging
Y Yang, Z Zeng, E Almatrafi, D Huang, C Zhang… - Coordination Chemistry …, 2022 - Elsevier
Photodynamic therapy (PDT) is an emerging noninvasive therapy modality for treating
cancer diseases. However, conventional PDT suffers from poor stability of organic …
cancer diseases. However, conventional PDT suffers from poor stability of organic …
An implantable active-targeting micelle-in-nanofiber device for efficient and safe cancer therapy
Nanocarriers have attracted broad attention in cancer therapy because of their ability to
carry drugs preferentially into cancer tissue, but their application is still limited due to the …
carry drugs preferentially into cancer tissue, but their application is still limited due to the …
[HTML][HTML] Single-versus dual-targeted nanoparticles with folic acid and biotin for anticancer drug delivery
M Jurczyk, K Jelonek, M Musiał-Kulik, A Beberok… - Pharmaceutics, 2021 - mdpi.com
Cancer is one of the major causes of death worldwide and its treatment remains very
challenging. The effectiveness of cancer therapy significantly depends upon tumour-specific …
challenging. The effectiveness of cancer therapy significantly depends upon tumour-specific …