Nonalcoholic steatohepatitis-related hepatocellular carcinoma: pathogenesis and treatment

JM Llovet, CE Willoughby, AG Singal… - Nature reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD), including its more severe manifestation,
nonalcoholic steatohepatitis (NASH), has a global prevalence of 20–25% and is a major …

Emerging therapeutic approaches for the treatment of NAFLD and type 2 diabetes mellitus

D Ferguson, BN Finck - Nature Reviews Endocrinology, 2021 - nature.com
Non-alcoholic fatty liver disease (NAFLD) has emerged as the most prevalent liver disease
in the world, yet there are still no approved pharmacological therapies to prevent or treat this …

Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention

DQ Huang, HB El-Serag, R Loomba - Nature reviews Gastroenterology …, 2021 - nature.com
One quarter of the global population is estimated to have nonalcoholic fatty liver disease
(NAFLD). The incidence of nonalcoholic steatohepatitis (NASH) is projected to increase by …

Global prevalence, incidence, and outcomes of non-obese or lean non-alcoholic fatty liver disease: a systematic review and meta-analysis

Q Ye, B Zou, YH Yeo, J Li, DQ Huang, Y Wu… - The lancet …, 2020 - thelancet.com
Background Although non-alcoholic fatty liver disease (NAFLD) is commonly associated
with obesity, it is increasingly being identified in non-obese individuals. We aimed to …

AGA clinical practice update: diagnosis and management of nonalcoholic fatty liver disease in lean individuals: expert review

MT Long, M Noureddin, JK Lim - Gastroenterology, 2022 - Elsevier
Description Nonalcoholic fatty liver disease (NAFLD) is well recognized as a leading
etiology for chronic liver disease, affecting> 25% of the US and global populations. Up to 1 …

[HTML][HTML] Alcohol consumption and metabolic syndrome: clinical and epidemiological impact on liver disease

F Åberg, CD Byrne, CJ Pirola, V Männistö… - Journal of …, 2023 - Elsevier
Alcohol use and metabolic syndrome are highly prevalent in the population and frequently
co-exist. Both are implicated in a large range of health problems, including chronic liver …

NAFLD‐related hepatocellular carcinoma: The growing challenge

PA Shah, R Patil, SA Harrison - Hepatology, 2023 - journals.lww.com
Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and
morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the …

Metabolic risk factors and incident advanced liver disease in non-alcoholic fatty liver disease (NAFLD): A systematic review and meta-analysis of population-based …

H Jarvis, D Craig, R Barker, G Spiers, D Stow… - PLoS …, 2020 - journals.plos.org
Background Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver
disease worldwide. Many individuals have risk factors associated with NAFLD, but the …

[PDF][PDF] 中国人群肝癌筛查指南(2022, 北京).

赫捷, 陈万青, 沈洪兵, 李霓, 曲春枫… - Journal of Clinical …, 2022 - xadxyylib.yuntsg.com
中国人群的肝癌存在生存率低, 死亡率高的情况, 如何有效降低肝癌相关负担仍是中国公共卫生
和慢性病防控领域亟待解决的重大问题, 而肝癌人群筛查策略优化是值得持续探索的重要抓手和 …

Non-alcoholic steatohepatitis: a review of its mechanism, models and medical treatments

C Peng, AG Stewart, OL Woodman… - Frontiers in …, 2020 - frontiersin.org
Non-alcoholic steatohepatitis (NASH) develops from non-alcoholic fatty liver disease
(NAFLD). Currently, around 25% of the population is estimated to have NAFLD, and 25% of …