[HTML][HTML] Interoceptive pathways to understand and treat mental health conditions
CL Nord, SN Garfinkel - Trends in Cognitive Sciences, 2022 - cell.com
An increasing recognition that brain and body are dynamically coupled has enriched our
scientific understanding of mental health conditions. Peripheral signals interact centrally to …
scientific understanding of mental health conditions. Peripheral signals interact centrally to …
[HTML][HTML] Inflammation-related functional and structural dysconnectivity as a pathway to psychopathology
Findings from numerous laboratories and across neuroimaging modalities have consistently
shown that exogenous administration of cytokines or inflammatory stimuli that induce …
shown that exogenous administration of cytokines or inflammatory stimuli that induce …
Interleukin-6 as potential mediator of long-term neuropsychiatric symptoms of COVID-19
The majority of COVID-19 survivors experience long-term neuropsychiatric symptoms such
as fatigue, sleeping difficulties, depression and anxiety. We propose that neuroimmune …
as fatigue, sleeping difficulties, depression and anxiety. We propose that neuroimmune …
[HTML][HTML] New insights into the pivotal role of the amygdala in inflammation-related depression and anxiety disorder
P Hu, Y Lu, BX Pan, WH Zhang - International Journal of Molecular …, 2022 - mdpi.com
Depression and anxiety disorders are the two most prevalent psychiatric diseases that affect
hundreds of millions of individuals worldwide. Understanding the etiology and related …
hundreds of millions of individuals worldwide. Understanding the etiology and related …
[HTML][HTML] Functional connectivity in reward circuitry and symptoms of anhedonia as therapeutic targets in depression with high inflammation: evidence from a dopamine …
Increased inflammation in major depressive disorder (MDD) has been associated with low
functional connectivity (FC) in corticostriatal reward circuits and symptoms of anhedonia …
functional connectivity (FC) in corticostriatal reward circuits and symptoms of anhedonia …
Role of sleep quality in the acceleration of biological aging and its potential for preventive interaction on air pollution insults: Findings from the UK Biobank cohort
Sleep has been associated with aging and relevant health outcomes, but the causal
relationship remains inconclusive. In this study, we investigated the associations of sleep …
relationship remains inconclusive. In this study, we investigated the associations of sleep …
Metabolomic and inflammatory signatures of symptom dimensions in major depression
CR Brydges, S Bhattacharyya, SM Dehkordi… - Brain, behavior, and …, 2022 - Elsevier
Background Major depressive disorder (MDD) is a highly heterogenous disease, both in
terms of clinical profiles and pathobiological alterations. Recently, immunometabolic …
terms of clinical profiles and pathobiological alterations. Recently, immunometabolic …
[HTML][HTML] The association between plasma tryptophan catabolites and depression: The role of symptom profiles and inflammation
Y Milaneschi, KA Allers, ATF Beekman, EJ Giltay… - Brain, behavior, and …, 2021 - Elsevier
Abstract Background Tryptophan catabolites (“TRYCATs”) produced by the kynurenine
pathway (KP) may play a role in depression pathophysiology. Studies comparing TRYCATs …
pathway (KP) may play a role in depression pathophysiology. Studies comparing TRYCATs …
[HTML][HTML] Role of inflammation in depression and anxiety: Tests for disorder specificity, linearity and potential causality of association in the UK Biobank
Z Ye, N Kappelmann, S Moser, GD Smith… - …, 2021 - thelancet.com
Background Concentrations of C-reactive protein (CRP), interleukin 6 (IL-6) and other
inflammatory markers are elevated in people with depression and anxiety compared to …
inflammatory markers are elevated in people with depression and anxiety compared to …
[HTML][HTML] Neuroinflammation in HIV-associated depression: Evidence and future perspectives
People living with HIV face a high risk of mental illness, especially depression. We do not yet
know the precise neurobiological mechanisms underlying HIV-associated depression …
know the precise neurobiological mechanisms underlying HIV-associated depression …