Metabolic programming and mitochondrial dynamics along with T cell differentiation affect T
cell fate and memory development; however, how to control metabolic reprogramming and …

Background Exposure to traffic pollution particulate matter, predominantly diesel exhaust
particles (DEPs), increases the risk of asthma and asthma exacerbation; however, the …

The impact of epigenetics on the differentiation of memory T (Tmem) cells is poorly defined.
We generated deep epigenomes comprising genome-wide profiles of DNA methylation …

T cells play a critical role in immune responses as they specifically recognize peptide/MHC
complexes with their T‐cell receptors and initiate adaptive immune responses. While T cells …

Lymphatic endothelial cells (LECs) chemoattract naïve T cells and promote their survival in
the lymph nodes, and can cross-present antigens to naïve CD8+ T cells to drive their …

In late 2013, the largest documented outbreak of Ebola hemorrhagic fever started in Guinea
and has since spread to neighboring countries, resulting in almost 27,000 cases and> …

Through positive selection, double‐positive cells in the thymus differentiate into CD4+ or
CD8+ T single‐positive cells that subsequently develop into different types of effective T …

The skin is our interface with the outside world, and consequently it is exposed to a wide
range of microbes and allergens. Recent studies have indicated that allergen-specific skin …

Babesia microti, an intraerythrocytic apicomplexan parasite, is the primary causative agent
of human babesiosis and an emerging threat to public health in the United States and …

Tuberculosis (TB) is the biggest cause of human mortality from an infectious disease. The
only vaccine currently available, bacille Calmette-Guérin (BCG), demonstrates some …