苯溴马隆与别嘌醇对心力衰竭伴高尿酸血症患者炎症因子及心功能的影响

单瑞, 程爱娟, 吴尚勤 - 中华高血压杂志, 2014 - cqvip.com
目的探讨苯溴马隆与别嘌醇对心力衰竭伴高尿酸血症患者炎症因子及心功能的影响.
方法连续人选2011 年9 月至2012 年9 月于天津市胸科医院治疗的心力衰竭伴高尿酸血症患者 …

Reduced mechanical efficiency of rat papillary muscle related to degree of hypertrophy of cardiomyocytes

YY Wong, ML Handoko… - American Journal …, 2010 - journals.physiology.org
Isolated rat papillary muscles of the right ventricle were used to discover the origin of
reduced myocardial efficiency in chronic heart failure. Right ventricular hypertrophy was …

Therapeutic effects of allopurinol on the function of left ventricular and activity of matrix metalloproteinase enzymes (MMPs) in patients with chronic heart failure

H Deng, Q Li, D Zhu - Cellular and Molecular Biology, 2022 - cellmolbiol.org
Heart failure is a growing public health problem, especially in the elderly, often occurring
due to ischemia and coronary artery disease. Allopurinol can protect against myocardial …

Targeted antioxidant treatment decreases cardiac alternans associated with chronic myocardial infarction

BN Plummer, H Liu, X Wan, I Deschênes… - Circulation: Arrhythmia …, 2015 - Am Heart Assoc
Background—In myocardial infarction (MI), repolarization alternans is a potent arrhythmia
substrate that has been linked to Ca2+ cycling proteins, such as sarcoplasmic reticulum …

Acute effects of febuxostat, a nonpurine selective inhibitor of xanthine oxidase, in pacing induced heart failure

M Hou, Q Hu, Y Chen, L Zhao, J Zhang… - Journal of …, 2006 - journals.lww.com
We investigated whether xanthine oxidase inhibition with febuxostat enhances left
ventricular (LV) function and improves myocardial high energy phosphates (HEP) in dogs …

Nitric oxide and related factors linked to oxidation and inflammation as possible biomarkers of heart failure

R Bonafede, W Manucha - Clínica e Investigación en Arteriosclerosis …, 2018 - Elsevier
As a prevalent cardiovascular disease, heart failure is one of the leading causes of morbidity
and premature mortality. Therefore, there is a special interest in the study of efficient markers …

Purine nucleoside phosphorylase and xanthine oxidase activities in erythrocytes and plasma from marine, semiaquatic and terrestrial mammals

RI López-Cruz, MB Pérez-Milicua, DE Crocker… - … and Physiology Part A …, 2014 - Elsevier
Purine nucleoside phosphorylase (PNP) and xanthine oxidase (XO) are key enzymes
involved in the purine salvage pathway. PNP metabolizes purine bases to synthetize purine …

Allopurinol and endothelial function in heart failure: future or fantasy?

U Landmesser, H Drexler - Circulation, 2002 - Am Heart Assoc
The endothelium plays an important role in the control of vascular tone by releasing both
vasodilating and vasoconstricting substances. These mechanisms are important for the …

Acylated ghrelin protection inhibits apoptosis in the remote myocardium post-myocardial infarction by inhibiting calcineurin and activating ARC

RA Eid - Archives of Physiology and Biochemistry, 2024 - Taylor & Francis
This study investigated if acylated ghrelin (AG) could inhibit myocardial infarction (MI)-
induced apoptosis in the left ventricles (LV) of male rats and tested if this protection involves …

[HTML][HTML] Ameliorative effect of allopurinol on vascular complications of insulin resistance

HM El-Bassossy, AA Elberry, A Azhar… - Journal of diabetes …, 2015 - hindawi.com
The aim of the current study was to evaluate the possible protective effect of allopurinol
(Allo) on experimentally induced insulin resistance (IR) and vascular complications. Rats …