Genomic and proteomic studies have helped improve our understanding of the underlying
mechanism (s) of cancer development and progression. Mutations, overexpressed …

Multidrug resistance (MDR) to anticancer drugs remains a serious obstacle to the success of
cancer chemotherapy. Resveratrol, a polyphenol, present in natural products exerts …

Background Breast cancer stands as the most common malignancy among women globally
and a leading cause of cancer-related mortality. Conventional treatments, such as surgery …

Background Over the last decade resveratrol has been trialled for the prevention and
treatment of cognitive decline; however, the results have shown a conflict between human …

While preclinical studies suggest the breast cancer (BC) chemopreventive effects of dietary
polyphenols, the human evidence is still very weak. The huge existing in vitro–in vivo gap is …

Estrogen plays a pivotal role in the pathological development of breast cancer. Resveratrol
has chemo-preventive effects against breast cancer, whereas, the mechanism of antitumor …

Prodrugs of resveratrol are under development. Among the long‐term goals, still largely
elusive, are (1) modulating physical properties (eg, water‐soluble derivatives bearing …

Resveratrol is a drug with high potential for clinical application based on experimental
models. Though, resveratrol translation to clinical use has not been successful yet due to its …

Background: Gastric Cancer (GC) is one of the most malignant and lethal tumors worldwide.
The hypoxic microenvironment is correlated with GC cell invasion, metastasis and Epithelial …

Doxorubicin (Doxo) is the most effective chemotherapeutic agent for the treatment of breast
cancer. However, resistance to Doxo is common. Adjuvant compounds capable of …