Role of cholinergic signaling in Alzheimer's disease
ZR Chen, JB Huang, SL Yang, FF Hong - Molecules, 2022 - mdpi.com
Acetylcholine, a neurotransmitter secreted by cholinergic neurons, is involved in signal
transduction related to memory and learning ability. Alzheimer's disease (AD), a progressive …
transduction related to memory and learning ability. Alzheimer's disease (AD), a progressive …
Alzheimer's disease pharmacotherapy in relation to cholinergic system involvement
GD Stanciu, A Luca, RN Rusu, V Bild… - Biomolecules, 2019 - mdpi.com
Alzheimer's disease, a major and increasing global health challenge, is an irreversible,
progressive form of dementia, associated with an ongoing decline of brain functioning. The …
progressive form of dementia, associated with an ongoing decline of brain functioning. The …
Potential and limits of cannabinoids in Alzheimer's disease therapy
Simple Summary This review was aimed at exploring the potentiality of drugging the
endocannabinoid system as a therapeutic option for Alzheimer's disease (AD). Recent …
endocannabinoid system as a therapeutic option for Alzheimer's disease (AD). Recent …
Recent advances in the potential of cannabinoids for neuroprotection in Alzheimer's, Parkinson's, and Huntington's diseases
Three prevalent neurodegenerative diseases, Parkinson's, Alzheimer's, and Huntington's
are in need of symptomatic relief of slowing disease progression or both. This chapter …
are in need of symptomatic relief of slowing disease progression or both. This chapter …
Age and gender differences for the behavioral phenotypes of 3xTg Alzheimer's disease mice
The triple transgenic Alzheimer's disease (3xTg-AD) strain is a common mouse model used
for studying the pathology and mechanism of Alzheimer's disease (AD). The 3xTg-AD strain …
for studying the pathology and mechanism of Alzheimer's disease (AD). The 3xTg-AD strain …
Crosstalk between the M1 muscarinic acetylcholine receptor and the endocannabinoid system: A relevance for Alzheimer's disease?
KJ Thompson, AB Tobin - Cellular Signalling, 2020 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder which accounts for 60–70% of the
50 million worldwide cases of dementia and is characterised by cognitive impairments …
50 million worldwide cases of dementia and is characterised by cognitive impairments …
Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams–Beuren syndrome
A Navarro-Romero, L Galera-López, P Ortiz-Romero… - Elife, 2022 - elifesciences.org
Williams–Beuren syndrome (WBS) is a rare genetic multisystemic disorder characterized by
mild-to-moderate intellectual disability and hypersocial phenotype, while the most …
mild-to-moderate intellectual disability and hypersocial phenotype, while the most …
Modulation of neurolipid signaling and specific lipid species in the triple transgenic mouse model of Alzheimer's disease
E González de San Román, A Llorente-Ovejero… - International journal of …, 2021 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most
common cause of dementia in aging populations. Recently, the regulation of neurolipid …
common cause of dementia in aging populations. Recently, the regulation of neurolipid …
Cannabinoid receptors and glial response following a basal forebrain cholinergic lesion
A Llorente-Ovejero, I Bengoetxea de Tena… - ACS Pharmacology & …, 2022 - ACS Publications
The endocannabinoid system modulates learning, memory, and neuroinflammatory
processes, playing a key role in neurodegeneration, including Alzheimer's disease (AD) …
processes, playing a key role in neurodegeneration, including Alzheimer's disease (AD) …
On the biomedical properties of endocannabinoid degradation and reuptake inhibitors: pre-clinical and clinical evidence
KJ Paredes-Ruiz, K Chavira-Ramos… - Neurotoxicity …, 2021 - Springer
The endocannabinoid system (ECS) is composed of endogenous cannabinoids;
components involved in their synthesis, transport, and degradation; and an expansive …
components involved in their synthesis, transport, and degradation; and an expansive …