Inbred mouse strains provide genetic diversity comparable to that of the human population.
Like humans, mice have a wide range of diabetes-related phenotypes. The inbred mouse …

Several genes that predispose to type 2 diabetes have recently been identified. In addition
to the recognized and powerful effects of environmental factors, there is abundant evidence …

Objectives. We investigated whether racial disparities in the prevalence of type 2 diabetes
exist beyond what may be attributable to differences in socioeconomic status (SES) and …

Transient neonatal diabetes mellitus (TNDM) is a rare inherited diabetic syndrome apparent
in the first weeks of life and again during early adulthood. The relative contributions of …

Genome-wide experimental methods to identify disease genes, such as linkage analysis
and association studies, generate increasingly large candidate gene sets for which …

OBJECTIVE—A small number of susceptibility genes for human type 2 diabetes have been
identified by candidate gene analysis or positional cloning. Genes found to influence …

Migraine and glucose-related (glycaemic) traits (fasting glucose, fasting insulin, and type 2
diabetes) are common and complex comorbid disorders that cause major economic and …

OBJECTIVE—We previously detected an association between a region of the estrogen
receptor-α (ESR1) gene and type 2 diabetes in an African-American case-control study; …

The prevalence of type 2 diabetes (T2D) is greater in populations of African descent
compared to European-descent populations. Genetic risk factors may underlie the disparity …

OBJECTIVE—Diabetic nephropathy, the most common cause of end-stage renal disease,
aggregates in families and specific ethnic groups. Deconstructing diabetic nephropathy into …