Advancements in NSCLC: From Pathophysiological Insights to Targeted Treatments

J Xu, L Tian, W Qi, Q Lv, T Wang - American Journal of Clinical …, 2024 - journals.lww.com
With the global incidence of non-small cell lung cancer (NSCLC) on the rise, the
development of innovative treatment strategies is increasingly vital. This review underscores …

A study on optical properties of various hot drug molecules by 2020

C Zhang, Y Yang, X Yan, YT Sun, A Shao… - New Journal of …, 2023 - pubs.rsc.org
Advances in imaging technologies and imaging probes for in situ and real-time visualization
of important analytes and biological events in humans are now extending the applications of …

Spectral, XRD, morphological, DFT, and molecular modeling investigations of newly prepared isatin Schiff base complexes

BS Moustafa, MM Omar, WS Qayed… - Applied …, 2024 - Wiley Online Library
The new Schiff base ligand was designed from a condensation reaction of isatin with 5‐
amino‐2‐hydroxy benzoic acid. Then, the metal complexes were prepared. The structures of …

Synthesis of new Michael acceptors with cinnamamide scaffold as potential anti-breast cancer agents: cytotoxicity and ADME in silico studies

RP Paulino, RB Alves, H Silva… - Medicinal Chemistry …, 2024 - Springer
In pursuit of potent inhibitors with antiproliferative effects against breast cancer, fifteen new
compounds containing a Michael Acceptor Moiety (MAM) were synthesized. The …

Design, synthesis, and antitumor activity of benzimidazole derivatives as CDK4/6 inhibitors

XJ Wang, X Hou, LY Zhang, BY Wang, M Wu… - Journal of Molecular …, 2024 - Elsevier
A series of benzimidazole derivatives were synthesized and characterized using 1 H NMR,
13 C NMR, HR-MS, FTIR and UV Vis. The cytotoxicity of these compounds was evaluated …