Atherosclerosis and inflammation: insights from the theory of general pathological processes

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Integrin signaling in cancer: bidirectional mechanisms and therapeutic opportunities

S Li, C Sampson, C Liu, H Piao, HX Liu - Cell Communication and …, 2023 - Springer
Integrins are transmembrane receptors that possess distinct ligand-binding specificities in
the extracellular domain and signaling properties in the cytoplasmic domain. While most …

Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions

P Lu, D Ruan, M Huang, M Tian, K Zhu… - … and Targeted Therapy, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

Inflammation-mediated matrix remodeling of extracellular matrix-mimicking biomaterials in tissue engineering and regenerative medicine

M Xu, T Su, X Jin, Y Li, Y Yao, K Liu, K Chen, F Lu… - Acta Biomaterialia, 2022 - Elsevier
Extracellular matrix (ECM)-mimicking biomaterials are considered effective tissue-
engineered scaffolds for regenerative medicine because of their biocompatibility …

Therapeutic Role and Potential Mechanism of Resveratrol in Atherosclerosis: TLR4/NF‐κB/HIF‐1α

L Guo, X Zhang, N Lv, L Wang, J Gan… - Mediators of …, 2023 - Wiley Online Library
Atherosclerosis, the main pathological basis of cardiovascular disease, is a chronic
inflammatory disease that severely affects the quality of human life. Resveratrol (Res) is a …

[HTML][HTML] Macrophage-related therapeutic strategies: regulation of phenotypic switching and construction of drug delivery systems

X Wang, Y Li, X Pu, G Liu, H Qin, W Wan, Y Wang… - Pharmacological …, 2023 - Elsevier
Macrophages, as highly phenotypic plastic immune cells, play diverse roles in different
pathological conditions. Changing and controlling the phenotypes of macrophages is …

The influence of microenvironment stiffness on endothelial cell fate: Implication for occurrence and progression of atherosclerosis

L Cheng, H Yue, H Zhang, Q Liu, L Du, X Liu, J Xie… - Life Sciences, 2023 - Elsevier
Atherosclerosis, the primary cause of cardiovascular diseases (CVDs), is characterized by
phenotypic changes in fibrous proliferation, chronic inflammation and lipid accumulation …

[HTML][HTML] Biophysical cues to improve the immunomodulatory capacity of mesenchymal stem cells: the progress and mechanisms

Q Gao, F Jia, X Li, Y Kong, Z Tian, L Bi, L Li - Biomedicine & …, 2023 - Elsevier
Mesenchymal stem cells (MSCs) can maintain immune homeostasis and many preclinical
trials with MSCs have been carried out around the world. In vitro culture of MSCs has been …

Potential effects of biomaterials on macrophage function and their signalling pathways

F Zhu, S Wang, X Zhu, C Pang, P Cui, F Yang… - Biomaterials …, 2023 - pubs.rsc.org
The use of biomaterials in biomedicine and healthcare has increased in recent years.
Macrophages are the primary immune cells that induce inflammation and tissue repair after …

Mechanosensing and mechanosignal transduction in atherosclerosis

SG Rahaman, M Mahanty, P Mukherjee, B Dutta… - Current Atherosclerosis …, 2023 - Springer
Abstract Purpose of Review This review aims to summarize the latest findings on
mechanosensing in atherosclerosis, elucidating the molecular mechanisms, cellular players …