[HTML][HTML] Mother-to-child HTLV-1 transmission: unmet research needs

C Rosadas, GP Taylor - Frontiers in microbiology, 2019 - frontiersin.org
Mother-to-child transmission (MTCT) of Human T-cell lymphotropic virus type 1 (HTLV-1)
causes lifelong infection. At least 5–10 million individuals worldwide are currently living with …

[HTML][HTML] Epidemiology of HTLV-1 infection and ATL in Japan: an update

M Iwanaga - Frontiers in microbiology, 2020 - frontiersin.org
Adult T-cell leukemia-lymphoma (ATL) is an aggressive T-cell malignancy caused by human
T-cell leukemia virus type 1 (HTLV-1) infection that often occurs in HTLV-1-endemic areas …

Rapid progression of adult T-cell leukemia/lymphoma as tumor-infiltrating Tregs after PD-1 blockade

DA Rauch, KC Conlon, M Janakiram… - Blood, The Journal …, 2019 - ashpublications.org
Immune checkpoint inhibitors are a powerful new tool in the treatment of cancer, with
prolonged responses in multiple diseases, including hematologic malignancies, such as …

Human T cell leukemia virus type 1: persistence and pathogenesis

CRM Bangham - Annual review of immunology, 2018 - annualreviews.org
Human T cell leukemia virus type 1 (HTLV-1), also known as human T lymphotropic virus
type 1, was the first exogenous human retrovirus discovered. Unlike the distantly related …

[HTML][HTML] Geographic distribution, clinical epidemiology and genetic diversity of the human oncogenic retrovirus HTLV-1 in Africa, the world's largest endemic area

A Gessain, JL Ramassamy, PV Afonso… - Frontiers in …, 2023 - frontiersin.org
The African continent is considered the largest high endemic area for the oncogenic
retrovirus HTLV-1 with an estimated two to five million infected individuals. However, data on …

[HTML][HTML] HTLV-1, the other pathogenic yet neglected human retrovirus: from transmission to therapeutic treatment

N Futsch, R Mahieux, H Dutartre - Viruses, 2017 - mdpi.com
Going back to their discovery in the early 1980s, both the Human T-cell Leukemia virus type-
1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the …

[HTML][HTML] An update on human T-cell leukemia virus type I (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) focusing on clinical and laboratory …

J Yamauchi, N Araya, N Yagishita, T Sato… - Pharmacology & …, 2021 - Elsevier
Human T-cell leukemia virus type I (HTLV-1)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a rare inflammatory disease causing unremitting and progressive …

Integrated molecular and immunological features of human T-lymphotropic virus type 1 infection and disease progression to adult T-cell leukaemia or lymphoma

JS O'Donnell, SK Hunt, KJ Chappell - The Lancet Haematology, 2023 - thelancet.com
The human T-lymphotropic virus type 1 (HTLV-1) retrovirus infects 10–20 million people
globally, with endemic regions in southwestern Japan, the Caribbean basin, Africa, and …

[HTML][HTML] Characterization of novel Bovine Leukemia Virus (BLV) antisense transcripts by deep sequencing reveals constitutive expression in tumors and transcriptional …

K Durkin, N Rosewick, M Artesi, V Hahaut, P Griebel… - Retrovirology, 2016 - Springer
Abstract Background Bovine Leukemia Virus (BLV) is a deltaretrovirus closely related to the
Human T cell leukemia virus-1 (HTLV-1). Cattle are the natural host of BLV where it …

HTLV-1 persistence and the oncogenesis of adult T-cell leukemia/lymphoma

CRM Bangham - Blood, The Journal of the American Society of …, 2023 - ashpublications.org
Human T-cell leukemia virus type I (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL)
in 5% of infected people with a decades-long latency. Charles RM Bangham reviews the …